The 20 references with contexts in paper A. Mokhov A., A. Murashev N., M. Krasilshchikova S., O. Khokhlova N., S. Semushina G., E. Rasskazova A., D. Rzhevskiy I., V. Popov S., A. Yavorsky N., А. Мохов А., А. Мурашев Н., М. Красильщикова С., О. Хохлова Н., С. Семушина Г., Е. Рассказова А., Д. Ржевский И., В. Попов С., А. Яворский Н. (2018) “О необходимости совершенствования законодательства в сфере использования лабораторных животных // On the need to improve the legislation on laboratory animals” / spz:neicon:vedomostincesmp:y:2016:i:4:p:62-68

1
Anisimov AP, Mokhov AA, Kopylov DE. Animals as objects of civil and other legal relations. Sovremennoe pravo 2007; (4): 93–8 (in Russian).
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    Âûñêàçûâàþòñÿ ïðåäëîæåíèÿ çàêðåïèòü îñîáåííîñòè æèâîòíûõ êàê îáúåêòîâ ïðàâîîòíîøåíèé, à òàêæå óðåãóëèðîâàòü êîìïëåêñ ñëîæíûõ îáùåñòâåííûõ îòíîøåíèé, âîçíèêàþùèõ â ñâÿçè ñ èõ ñîäåðæàíèåì è èñïîëüçîâàíèåì
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    . Â íàñòîÿùåå âðåìÿ æèâîòíûì êàê îáúåêòàì ïîñâÿùåíà ñò. 137 Ãðàæäàíñêîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè [3], à òàêæå ñò. 245 Óãîëîâíîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè [4]. Ãðàæäàíñêèé êîäåêñ ïðèðàâíèâàåò æèâîòíûõ ê èìóùåñòâó, â îòíîøåíèè êîòîðîãî ìîãóò áûòü óñòàíîâëåíû íåêîòîðûå îñîáåííîñòè åãî èñïîëüçîâàíèÿ, à Óãîëîâíûé êîäåêñ ïðåäóñìàòðèâàåò óãîëîâíóþ îòâåòñòâåííîñòü çà æåñòîêîå îáðàùåíèå ñ æèâî

2
Mikryukov VA. Animals as a special object property burden. Yuridicheskiy mir 2016; (5): 32–5 (in Russian).
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    Âûñêàçûâàþòñÿ ïðåäëîæåíèÿ çàêðåïèòü îñîáåííîñòè æèâîòíûõ êàê îáúåêòîâ ïðàâîîòíîøåíèé, à òàêæå óðåãóëèðîâàòü êîìïëåêñ ñëîæíûõ îáùåñòâåííûõ îòíîøåíèé, âîçíèêàþùèõ â ñâÿçè ñ èõ ñîäåðæàíèåì è èñïîëüçîâàíèåì
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    . Â íàñòîÿùåå âðåìÿ æèâîòíûì êàê îáúåêòàì ïîñâÿùåíà ñò. 137 Ãðàæäàíñêîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè [3], à òàêæå ñò. 245 Óãîëîâíîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè [4]. Ãðàæäàíñêèé êîäåêñ ïðèðàâíèâàåò æèâîòíûõ ê èìóùåñòâó, â îòíîøåíèè êîòîðîãî ìîãóò áûòü óñòàíîâëåíû íåêîòîðûå îñîáåííîñòè åãî èñïîëüçîâàíèÿ, à Óãîëîâíûé êîäåêñ ïðåäóñìàòðèâàåò óãîëîâíóþ îòâåòñòâåííîñòü çà æåñòîêîå îáðàùåíèå ñ æèâî

3
The Civil Code of the Russian Federation. Part One. Federal Law of the Russian Federation, November 30, 1994, ¹ 51-FZ (in Russian).
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    Âûñêàçûâàþòñÿ ïðåäëîæåíèÿ çàêðåïèòü îñîáåííîñòè æèâîòíûõ êàê îáúåêòîâ ïðàâîîòíîøåíèé, à òàêæå óðåãóëèðîâàòü êîìïëåêñ ñëîæíûõ îáùåñòâåííûõ îòíîøåíèé, âîçíèêàþùèõ â ñâÿçè ñ èõ ñîäåðæàíèåì è èñïîëüçîâàíèåì [1, 2]. Â íàñòîÿùåå âðåìÿ æèâîòíûì êàê îáúåêòàì ïîñâÿùåíà ñò. 137 Ãðàæäàíñêîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè
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    , à òàêæå ñò. 245 Óãîëîâíîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè [4]. Ãðàæäàíñêèé êîäåêñ ïðèðàâíèâàåò æèâîòíûõ ê èìóùåñòâó, â îòíîøåíèè êîòîðîãî ìîãóò áûòü óñòàíîâëåíû íåêîòîðûå îñîáåííîñòè åãî èñïîëüçîâàíèÿ, à Óãîëîâíûé êîäåêñ ïðåäóñìàòðèâàåò óãîëîâíóþ îòâåòñòâåííîñòü çà æåñòîêîå îáðàùåíèå ñ æèâîòíûìè.

4
The Criminal Code of the Russian Federation. Federal Law of the Russian Federation, June 30, 1996, ¹ 63-FZ (in Russian).
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    Âûñêàçûâàþòñÿ ïðåäëîæåíèÿ çàêðåïèòü îñîáåííîñòè æèâîòíûõ êàê îáúåêòîâ ïðàâîîòíîøåíèé, à òàêæå óðåãóëèðîâàòü êîìïëåêñ ñëîæíûõ îáùåñòâåííûõ îòíîøåíèé, âîçíèêàþùèõ â ñâÿçè ñ èõ ñîäåðæàíèåì è èñïîëüçîâàíèåì [1, 2]. Â íàñòîÿùåå âðåìÿ æèâîòíûì êàê îáúåêòàì ïîñâÿùåíà ñò. 137 Ãðàæäàíñêîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè [3], à òàêæå ñò. 245 Óãîëîâíîãî êîäåêñà Ðîññèéñêîé Ôåäåðàöèè
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    . Ãðàæäàíñêèé êîäåêñ ïðèðàâíèâàåò æèâîòíûõ ê èìóùåñòâó, â îòíîøåíèè êîòîðîãî ìîãóò áûòü óñòàíîâëåíû íåêîòîðûå îñîáåííîñòè åãî èñïîëüçîâàíèÿ, à Óãîëîâíûé êîäåêñ ïðåäóñìàòðèâàåò óãîëîâíóþ îòâåòñòâåííîñòü çà æåñòîêîå îáðàùåíèå ñ æèâîòíûìè.

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Federal Law of the Russian Federation, January 10, 2002, ¹ 7-FZ «On Environmental Protection» (in Russian).
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    Ãðàæäàíñêèé êîäåêñ ïðèðàâíèâàåò æèâîòíûõ ê èìóùåñòâó, â îòíîøåíèè êîòîðîãî ìîãóò áûòü óñòàíîâëåíû íåêîòîðûå îñîáåííîñòè åãî èñïîëüçîâàíèÿ, à Óãîëîâíûé êîäåêñ ïðåäóñìàòðèâàåò óãîëîâíóþ îòâåòñòâåííîñòü çà æåñòîêîå îáðàùåíèå ñ æèâîòíûìè. Ñëåäóåò òàêæå óïîìÿíóòü ñò. 60 Ôåäåðàëüíîãî çàêîíà Ðîññèéñêîé Ôåäåðàöèè îò 10 ÿíâàðÿ 2002 ã. ¹ 7-ÔÇ «Îá îõðàíå îêðóæàþùåé ñðåäû »
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    , íàïðàâëåííóþ íà îáåñïå÷åíèå îõðàíû ðåäêèõ è íàõîäÿùèõñÿ ïîä óãðîçîé èñ÷åçíîâåíèÿ æèâîòíûõ. Íàðÿäó ñ îáùèìè ïðîáëåìàìè, èìåþòñÿ è ÷àñòíûå, íî íå ìåíåå çíà÷èìûå ïðîáëåìû èñïîëüçîâàíèÿ æèâîòíûõ. Ê òàêîâûì, âíå âñÿêîãî ñîìíåíèÿ, îòíîñÿòñÿ ëàáîðàòîðíûå æèâîòíûå.

6
Kopylov DE, Maslov VV. Public interest in the legal relationship on the use of laboratory animals in the Russian Federation. Vestnik Samarskogo gosudarstvennogo ekonomicheskogo universiteta 2006; (8): 225–7 (in Russian).
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    Ê òàêîâûì, âíå âñÿêîãî ñîìíåíèÿ, îòíîñÿòñÿ ëàáîðàòîðíûå æèâîòíûå. Â ñïåöèàëüíîé ëèòåðàòóðå ïðåäëàãàëîñü äàòü íîðìàòèâíîå ïîíÿòèå îòäåëüíûõ âèäîâ æèâîòíûõ (ëàáîðàòîðíûõ, òðàíñãåííûõ, ýêñïåðèìåíòàëüíûõ), îïðåäåëèòü îòäåëüíûå îñîáåííîñòè èõ èñïîëüçîâàíèÿ
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    . Îäíàêî äî íàñòîÿùåãî âðåìåíè ñèòóàöèÿ íå ïðåòåðïåëà çíà÷èòåëüíûõ èçìåíåíèé.  2010 ãîäó â ÷. 5 ñò. 11 Ôåäåðàëüíîãî çàêîíà Ðîññèéñêîé Ôåäåðàöèè îò 12 àïðåëÿ 2010 ã. ¹ 61-ÔÇ «Îá îáðàùåíèè ëåêàðñòâåííûõ ñðåäñòâ »[7] áûëî çàêðåïëåíî, ÷òî ïðîâåäåíèå ïðîâåðîê ñîáëþäåíèÿ ïðàâèë ëàáîðàòîðíîé ïðàêòèêè è ïðàâîâûõ íîðì èñïîëüçîâàíèÿ æèâîòíûõ ïðè ïðîâåäåíèè äîêëèíè÷åñêèõ èññëåäîâàíèé ëåêàðñòâåííûõ ñðåäñòâ (

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Federal Law of the Russian Federation, April 12, 2010, ¹ 61-FZ «On Circulation of Medicines» (in Russian).
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    Îäíàêî äî íàñòîÿùåãî âðåìåíè ñèòóàöèÿ íå ïðåòåðïåëà çíà÷èòåëüíûõ èçìåíåíèé.  2010 ãîäó â ÷. 5 ñò. 11 Ôåäåðàëüíîãî çàêîíà Ðîññèéñêîé Ôåäåðàöèè îò 12 àïðåëÿ 2010 ã. ¹ 61-ÔÇ «Îá îáðàùåíèè ëåêàðñòâåííûõ ñðåäñòâ »
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    áûëî çàêðåïëåíî, ÷òî ïðîâåäåíèå ïðîâåðîê ñîáëþäåíèÿ ïðàâèë ëàáîðàòîðíîé ïðàêòèêè è ïðàâîâûõ íîðì èñïîëüçîâàíèÿ æèâîòíûõ ïðè ïðîâåäåíèè äîêëèíè÷åñêèõ èññëåäîâàíèé ëåêàðñòâåííûõ ñðåäñòâ (ËÑ) äëÿ ìåäèöèíñêîãî ïðèìåíåíèÿ îñóùåñòâëÿåòñÿ óïîëíîìî÷åííûì ôåäåðàëüíûì îðãàíîì èñïîëíèòåëüíîé âëàñòè.

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Federal Law of the Russian Federation, June 23, 2016, ¹ 180-FZ «On biomedical cell products» (in Russian).
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    »[7] áûëî çàêðåïëåíî, ÷òî ïðîâåäåíèå ïðîâåðîê ñîáëþäåíèÿ ïðàâèë ëàáîðàòîðíîé ïðàêòèêè è ïðàâîâûõ íîðì èñïîëüçîâàíèÿ æèâîòíûõ ïðè ïðîâåäåíèè äîêëèíè÷åñêèõ èññëåäîâàíèé ëåêàðñòâåííûõ ñðåäñòâ (ËÑ) äëÿ ìåäèöèíñêîãî ïðèìåíåíèÿ îñóùåñòâëÿåòñÿ óïîëíîìî÷åííûì ôåäåðàëüíûì îðãàíîì èñïîëíèòåëüíîé âëàñòè.  ÷. 1 ñò. 6 Ôåäåðàëüíîãî çàêîíà îò 23 èþíÿ 2016 ã. ¹ 180-ÔÇ «Î áèîìåäèöèíñêèõ êëåòî÷íûõ ïðîäóêòàõ »
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    òàêæå óêàçàíî, ÷òî äîêëèíè÷åñêîå èññëåäîâàíèå áèîìåäèöèíñêîãî êëåòî÷íîãî ïðîäóêòà ïðîâîäèòñÿ íà ìîäåëèðóåìûõ â îðãàíèçìå æèâîòíûõ ïàòîëîãè÷åñêèõ ïðîöåññàõ. Òàêèì îáðàçîì, ïîòðåáíîñòü â íîðìàòèâíîì äîêóìåíòå, ðåãëàìåíòèðóþùåì íàó÷íóþ ðàáîòó ñ æèâîòíûìè âî âñåõ ñôåðàõ ñîçäàíèÿ íîâûõ ËÑ, î÷åâèäíà, îäíàêî òàêîãî äîêóìåíòà äî ñèõ ïîð íåò.

9
Resolution of the Chief State Sanitary Doctor of the Russian Federation, August 29, 2014, ¹ 51 «On the approval of the joint venture 2.2.1.3218–14. «Sanitary requirements for design, equipment and maintenance of experimental biological clinics (vivariums)» (in Russian).
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    Ðàáîòà ñ ëàáîðàòîðíûìè æèâîòíûìè â Ðîññèè îñóùåñòâëÿåòñÿ íà îñíîâå ñëåäóþùèõ ïîäçàêîííûõ àêòîâ: ÑàíÏèÍ 2.2.1.3218–14 «Ñàíèòàðíî-ýïèäåìèîëîãè÷åñêèå òðåáîâàíèÿ ê óñòðîéñòâó, îáîðóäîâàíèþ è ñîäåðæàíèþ ýêñïåðèìåíòàëüíî-áèîëîãè÷åñêèõ êëèíèê (âèâàðèåâ) »è ÃÎÑÒ: ÃÎÑÒ 33215–2014 «Ïðàâèëà îáîðóäîâàíèÿ ïîìåùåíèé è îðãàíèçàöèè ïðîöåäóð ïðè ðàáîòå ñ ëàáîðàòîðíûìè æèâîòíûìè »
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    ; ÃÎÑÒ 33216–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè ãðûçóíàìè è êðîëèêàìè »[10]; ÃÎÑÒ 33217–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè õèùíûìè ìëåêîïèòàþùèìè »[11]; ÃÎÑÒ 33218–2014 «Ïðàâèëà ðàáîòû ñ íå÷åëîâåêîîáðàçíûìè ïðèìàòàìè »[12]; ÃÎÑÒ 33219–2014 «Ïðàâèëà ðàáîòû ñ ðûáàìè, àìôèáèÿìè è ðåïòèëèÿìè »[13].

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State Standart «Rules of work with laboratory rodents and rabbits» (in Russian).
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    íà îñíîâå ñëåäóþùèõ ïîäçàêîííûõ àêòîâ: ÑàíÏèÍ 2.2.1.3218–14 «Ñàíèòàðíî-ýïèäåìèîëîãè÷åñêèå òðåáîâàíèÿ ê óñòðîéñòâó, îáîðóäîâàíèþ è ñîäåðæàíèþ ýêñïåðèìåíòàëüíî-áèîëîãè÷åñêèõ êëèíèê (âèâàðèåâ) »è ÃÎÑÒ: ÃÎÑÒ 33215–2014 «Ïðàâèëà îáîðóäîâàíèÿ ïîìåùåíèé è îðãàíèçàöèè ïðîöåäóð ïðè ðàáîòå ñ ëàáîðàòîðíûìè æèâîòíûìè »[9]; ÃÎÑÒ 33216–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè ãðûçóíàìè è êðîëèêàìè »
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    ; ÃÎÑÒ 33217–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè õèùíûìè ìëåêîïèòàþùèìè »[11]; ÃÎÑÒ 33218–2014 «Ïðàâèëà ðàáîòû ñ íå÷åëîâåêîîáðàçíûìè ïðèìàòàìè »[12]; ÃÎÑÒ 33219–2014 «Ïðàâèëà ðàáîòû ñ ðûáàìè, àìôèáèÿìè è ðåïòèëèÿìè »[13].

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State Standart 33217–2014 «Rules of work with laboratory predatory mammals» (in Russian).
Total in-text references: 1
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    -ýïèäåìèîëîãè÷åñêèå òðåáîâàíèÿ ê óñòðîéñòâó, îáîðóäîâàíèþ è ñîäåðæàíèþ ýêñïåðèìåíòàëüíî-áèîëîãè÷åñêèõ êëèíèê (âèâàðèåâ) »è ÃÎÑÒ: ÃÎÑÒ 33215–2014 «Ïðàâèëà îáîðóäîâàíèÿ ïîìåùåíèé è îðãàíèçàöèè ïðîöåäóð ïðè ðàáîòå ñ ëàáîðàòîðíûìè æèâîòíûìè »[9]; ÃÎÑÒ 33216–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè ãðûçóíàìè è êðîëèêàìè »[10]; ÃÎÑÒ 33217–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè õèùíûìè ìëåêîïèòàþùèìè »
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    ; ÃÎÑÒ 33218–2014 «Ïðàâèëà ðàáîòû ñ íå÷åëîâåêîîáðàçíûìè ïðèìàòàìè »[12]; ÃÎÑÒ 33219–2014 «Ïðàâèëà ðàáîòû ñ ðûáàìè, àìôèáèÿìè è ðåïòèëèÿìè »[13]. Ïåðå÷èñëåííûå äîêóìåíòû â òîé èëè èíîé ìåðå îïîñðåäîâàííî ðåãóëèðóþò äåÿòåëüíîñòü ïî èñïîëüçîâàíèþ æèâîòíûõ â íàó÷íûõ öåëÿõ, – îò ïðîåêòèðîâàíèÿ è ñòðîèòåëüñòâà âèâàðèåâ, äî ïëàíèðîâàíèÿ ýêñïåðèìåíòîâ è ðàçâåäåíèÿ ëàáîðàòîðíûõ æèâîòíûõ.

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State Standart 33218–2014 «Rules for working with non-human primates» (in Russian).
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    ýêñïåðèìåíòàëüíî-áèîëîãè÷åñêèõ êëèíèê (âèâàðèåâ) »è ÃÎÑÒ: ÃÎÑÒ 33215–2014 «Ïðàâèëà îáîðóäîâàíèÿ ïîìåùåíèé è îðãàíèçàöèè ïðîöåäóð ïðè ðàáîòå ñ ëàáîðàòîðíûìè æèâîòíûìè »[9]; ÃÎÑÒ 33216–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè ãðûçóíàìè è êðîëèêàìè »[10]; ÃÎÑÒ 33217–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè õèùíûìè ìëåêîïèòàþùèìè »[11]; ÃÎÑÒ 33218–2014 «Ïðàâèëà ðàáîòû ñ íå÷åëîâåêîîáðàçíûìè ïðèìàòàìè »
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    ; ÃÎÑÒ 33219–2014 «Ïðàâèëà ðàáîòû ñ ðûáàìè, àìôèáèÿìè è ðåïòèëèÿìè »[13]. Ïåðå÷èñëåííûå äîêóìåíòû â òîé èëè èíîé ìåðå îïîñðåäîâàííî ðåãóëèðóþò äåÿòåëüíîñòü ïî èñïîëüçîâàíèþ æèâîòíûõ â íàó÷íûõ öåëÿõ, – îò ïðîåêòèðîâàíèÿ è ñòðîèòåëüñòâà âèâàðèåâ, äî ïëàíèðîâàíèÿ ýêñïåðèìåíòîâ è ðàçâåäåíèÿ ëàáîðàòîðíûõ æèâîòíûõ.

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State Standart 33219–2014 «Rules for working with fish, amphibians and reptiles» (in Russian).
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    –2014 «Ïðàâèëà îáîðóäîâàíèÿ ïîìåùåíèé è îðãàíèçàöèè ïðîöåäóð ïðè ðàáîòå ñ ëàáîðàòîðíûìè æèâîòíûìè »[9]; ÃÎÑÒ 33216–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè ãðûçóíàìè è êðîëèêàìè »[10]; ÃÎÑÒ 33217–2014 «Ïðàâèëà ðàáîòû ñ ëàáîðàòîðíûìè õèùíûìè ìëåêîïèòàþùèìè »[11]; ÃÎÑÒ 33218–2014 «Ïðàâèëà ðàáîòû ñ íå÷åëîâåêîîáðàçíûìè ïðèìàòàìè »[12]; ÃÎÑÒ 33219–2014 «Ïðàâèëà ðàáîòû ñ ðûáàìè, àìôèáèÿìè è ðåïòèëèÿìè »
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    [13]
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    . Ïåðå÷èñëåííûå äîêóìåíòû â òîé èëè èíîé ìåðå îïîñðåäîâàííî ðåãóëèðóþò äåÿòåëüíîñòü ïî èñïîëüçîâàíèþ æèâîòíûõ â íàó÷íûõ öåëÿõ, – îò ïðîåêòèðîâàíèÿ è ñòðîèòåëüñòâà âèâàðèåâ, äî ïëàíèðîâàíèÿ ýêñïåðèìåíòîâ è ðàçâåäåíèÿ ëàáîðàòîðíûõ æèâîòíûõ.

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Guidelines on the content of laboratory animals in the vivarium of researchinstitutesandeducationalinstitutionsRD-APK 3.10.07.02–09. Moscow: Ministry of Agriculture; 2009 (in Russian).
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     Ðîññèè ñóùåñòâóþò îòäåëüíûå óïîìèíàíèÿ àíåñòåçèè è àíàëãåçèè æèâîòíûõ. Íàïðèìåð, ñîãëàñíî ï. 6.32 «Ìåòîäè÷åñêèõ ðåêîìåíäàöèé ïî ñîäåðæàíèþ ëàáîðàòîðíûõ æèâîòíûõ â âèâàðèÿõ íàó÷íî-èññëåäîâàòåëüñêèõ èíñòèòóòîâ è ó÷åáíûõ çàâåäåíèé ÐÄ-ÀÏÊ 3.10.07.02–09 »
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    , â ñëó÷àÿõ, êîãäà ïðåäïîëàãàåòñÿ õèðóðãè÷åñêîå âìåøàòåëüñòâî èëè ïðîâåäåíèå ýêñïåðèìåíòà ñ áîëåâûì ðàçäðàæåíèåì, àíåñòåçèÿ äîëæíà ïðîâîäèòüñÿ äî ïðèâÿçûâàíèÿ æèâîòíîãî ê ñòàíêó. Ýâòàíàçèÿ.Îñíîâàíèÿ è óñëîâèÿ ýâòàíàçèè æèâîòíûõ â öåëîì íå çàêðåïëåíû çàêîíîäàòåëüíî.

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Guidelines MU 1.2.2745–10 «Procedure for the sampling characteristics of nanomaterials action on laboratory animals» (in Russian).
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    Èç äåéñòâóþùèõ â íàñòîÿùåå âðåìÿ íîðìàòèâíûõ äîêóìåíòîâ ýâòàíàçèÿ óïîìèíàåòñÿ â Ìåòîäè÷åñêèõ óêàçàíèÿõ ÌÓ 1.2.2745–10 «Ïîðÿäîê îòáîðà ïðîá äëÿ õàðàêòåðèñòèêè äåéñòâèÿ íàíîìàòåðèàëîâ íà ëàáîðàòîðíûõ æèâîòíûõ »
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    , êîòîðûå, â ñâîþ î÷åðåäü, îòñûëàþò íàñ ê ïðèêàçó Ìèíèñòåðñòâà çäðàâîîõðàíåíèÿ ÑÑÑÐ îò 12 àâãóñòà 1977 ã. ¹ 755 «Î ìåðàõ ïî äàëüíåéøåìó ñîâåðøåíñòâîâàíèþ îðãàíèçàöèîííûõ ôîðì ðàáîòû ñ èñïîëüçîâàíèåì ýêñïåðèìåíòàëüíûõ æèâîòíûõ »[20].

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Directive 2010/63/EU of the European parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes. Available from: http:// eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32010L0063.
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    Ïîìèìî îïðåäåëåíèÿ ëàáîðàòîðíûõ æèâîòíûõ, ïðåäñòàâëÿåòñÿ òàêæå öåëåñîîáðàçíûì îïðåäåëèòü è òî, ÷òî áóäåò ñ÷èòàòüñÿ «èñïîëüçîâàíèåì â íàó÷íûõ öåëÿõ». Çà îñíîâó ìîæíî âçÿòü ïåðå÷åíü, êîòîðûé ïðèâîäèòñÿ â Äèðåêòèâå Åâðîïåéñêîãî Ñîþçà 2010/63/EU
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    : a) ôóíäàìåíòàëüíûå èññëåäîâàíèÿ; á) òðàíñëÿöèîííûå èëè ïðèêëàäíûå èññëåäîâàíèÿ, ñòàâÿùèå ïåðåä ñîáîé îäíó èç ñëåäóþùèõ çàäà÷: (i) ïðåäîòâðàùåíèå, äèàãíîñòèêà è ëå÷åíèå çàáîëåâàíèé, íåäîìîãàíèé èëè äðóãèõ ïàòîëîãèé è èõ ïîñëåäñòâèé ó ÷åëîâåêà, æèâîòíûõ è ðàñòåíèé; (ii) îöåíêà, âûÿâëåíèå, êîíòðîëü è èçìåíåíèå ôèçèîëîãè÷åñêèõ ñîñòîÿíèé ÷åëîâåêà, æèâîòíûõ èëè ðàñòåíèé; (iii) áëàãîñîñòîÿíèå æèâîòíûõ

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    íà ëàáîðàòîðíûõ æèâîòíûõ »[15], êîòîðûå, â ñâîþ î÷åðåäü, îòñûëàþò íàñ ê ïðèêàçó Ìèíèñòåðñòâà çäðàâîîõðàíåíèÿ ÑÑÑÐ îò 12 àâãóñòà 1977 ã. ¹ 755 «Î ìåðàõ ïî äàëüíåéøåìó ñîâåðøåíñòâîâàíèþ îðãàíèçàöèîííûõ ôîðì ðàáîòû ñ èñïîëüçîâàíèåì ýêñïåðèìåíòàëüíûõ æèâîòíûõ »[20]. Ñëåäóåò èìåòü â âèäó, ÷òî ïðåäëàãàåìûå â ýòîì äîêóìåíòå ïðàâèëà ýâòàíàçèè íå ñîîòâåòñòâóþò äåéñòâóþùèì åâðîïåéñêèì íîðìàòèâàì
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    . Êîíå÷íûå òî÷êè. õîäå ýêñïåðèìåíòà, îñîáåííî åñëè îí ïðåäïîëàãàåò ñåðüåçíîå âìåøàòåëüñòâî â îðãàíèçì æèâîòíîãî, ôóíêöèîíàëüíûå ñèñòåìû æèâîòíûõ ìîãóò èçìåíèòüñÿ. Ïîýòîìó, íàðÿäó ñ êðèòåðèÿìè âêëþ÷åíèÿ æèâîòíûõ â ýêñïåðèìåíòàëüíóþ âûáîðêó, äîëæíû áûòü ÷åòêî ñôîðìóëèðîâàíû êðèòåðèè èñêëþ÷åíèÿ æèâîòíûõ èç ýêñïåðèìåíòà (êîíå÷íûå òî÷êè).

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Baker DG. Natural pathogens of laboratory animals: their effects on research. Washington DC: ASM Press; 2003.
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    Ïîä êà÷åñòâîì ïîíèìàþò, â ïåðâóþ î÷åðåäü, îïðåäåëåííûé ñòàòóñ çäîðîâüÿ æèâîòíûõ (îòñóòñòâèå èíôåêöèîííûõ àãåíòîâ, ñïîñîáíûõ èñêàçèòü ðåçóëüòàòû èññëåäîâàíèÿ), ãåíåòè÷åñêîå êà÷åñòâî æèâîòíûõ è îòñóòñòâèå äèñòðåññà.  íàñòîÿùèé ìîìåíò â íàó÷íîé ëèòåðàòóðå íàêîïëåí îáøèðíûé ìàòåðèàë ïî èíôåêöèîííûì çàáîëåâàíèÿì ëàáîðàòîðíûõ æèâîòíûõ
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    . Îñíîâíàÿ ïðîáëåìà äèàãíîñòèêè ýòèõ çàáîëåâàíèé çàêëþ÷àåòñÿ â òîì, ÷òî áîëüøèíñòâî èç íèõ ïðîòåêàþò ëàòåíòíî è â óäîâëåòâîðèòåëüíûõ óñëîâèÿõ íå äàþò êëèíè÷åñêèõ ïðîÿâëåíèé, ïî êðàéíåé ìåðå, ó èììóíîêîìïåòåíòíûõ æèâîòíûõ.

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FELASA recommendations for the health monitoring of mouse, rat, hamster, guinea pig and rabbit colonies in breeding and experimental units. Lab Anim. 2014; 48(3): 178–92.
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    îðãàíèçàöèè ñ äâóìÿ ïðèíöèïèàëüíûìè îãîâîðêàìè: – îí îáÿçàòåëüíî äîëæåí áûòü ñôîðìèðîâàí; – ïèòîìíèêè äîëæíû ïðåäîñòàâëÿòü æèâîòíûõ ñ ñàìûì ïîëíûì ëèñòîì èñêëþ÷åíèÿ (â êà÷åñòâå îðèåíòèðà ìîæíî âçÿòü àêòóàëüíûé ëèñò èñêëþ÷åíèÿ Ôåäåðàöèè åâðîïåéñêèõ àññîöèàöèé ñïåöèàëèñòîâ â îáëàñòè íàóêè î ëàáîðàòîðíûõ æèâîòíûõ (Federation of European Laboratory Animal Science Associations, FELASA
    Exact
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    ). Ãîâîðÿ î ãåíåòè÷åñêîì êà÷åñòâå æèâîòíûõ, íóæíî èìåòü â âèäó ñëåäóþùåå. Áîëüøèíñòâî æèâîòíûõ — áèîëîãè÷åñêèõ ìîäåëåé ïàòîëîãè÷åñêèõ ñîñòîÿíèé ÷åëîâåêà ñîçäàíû öåëåíàïðàâëåííî ïóòåì ñåëåêöèè èëè íàïðàâëåííîãî èçìåíåíèÿ ãåíîìà è ïîñëåäóþùåãî ñêðåùèâàíèÿ ïî ñòðîãî îïðåäåëåííûì ïðàâèëàì.

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FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents. Lab Anim. 2013; 47(3): 134–45.
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     ñîâðåìåííîé íàó÷íîé ïðàêòèêå ïîëó÷èëè øèðîêîå ðàñïðîñòðàíåíèå ìåòîäèêè ïðèæèçíåííîãî ãåíîòèïèðîâàíèÿ æèâîòíûõ, ÷òî ïîçâîëÿåò â ñëó÷àå êàæäîãî êîíêðåòíîãî èññëåäîâàíèÿ ïîäòâåðäèòü ãåíåòè÷åñêèé ñòàòóñ áèîëîãè÷åñêèõ ìîäåëåé
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    . Ãåíîòèïèðîâàíèå äîëæíî áûòü îáÿçàòåëüíûì òðåáîâàíèåì äëÿ ïèòîìíèêîâ ëàáîðàòîðíûõ æèâîòíûõ. Ê çíà÷èòåëüíîìó èñêàæåíèþ ýêñïåðèìåíòàëüíûõ äàííûõ ìîæåò ïðèâîäèòü òàêæå è ñîñòîÿíèå äèñòðåññà, èñïûòûâàåìîå æèâîòíûìè â íàó÷íîé îðãàíèçàöèè.

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Order of the USSR Ministry of Health, August 12, 1977, ¹ 755 «On measures to further improve theorganizational work using experimental animals» (in Russian). AUTHORS Kutafin Moscow State Law University (MSAL), Sadovaya-Kudrinskaya street 9, Moscow 125993, Russian Federation.
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    äîêóìåíòîâ ýâòàíàçèÿ óïîìèíàåòñÿ â Ìåòîäè÷åñêèõ óêàçàíèÿõ ÌÓ 1.2.2745–10 «Ïîðÿäîê îòáîðà ïðîá äëÿ õàðàêòåðèñòèêè äåéñòâèÿ íàíîìàòåðèàëîâ íà ëàáîðàòîðíûõ æèâîòíûõ »[15], êîòîðûå, â ñâîþ î÷åðåäü, îòñûëàþò íàñ ê ïðèêàçó Ìèíèñòåðñòâà çäðàâîîõðàíåíèÿ ÑÑÑÐ îò 12 àâãóñòà 1977 ã. ¹ 755 «Î ìåðàõ ïî äàëüíåéøåìó ñîâåðøåíñòâîâàíèþ îðãàíèçàöèîííûõ ôîðì ðàáîòû ñ èñïîëüçîâàíèåì ýêñïåðèìåíòàëüíûõ æèâîòíûõ »
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    . Ñëåäóåò èìåòü â âèäó, ÷òî ïðåäëàãàåìûå â ýòîì äîêóìåíòå ïðàâèëà ýâòàíàçèè íå ñîîòâåòñòâóþò äåéñòâóþùèì åâðîïåéñêèì íîðìàòèâàì [16]. Êîíå÷íûå òî÷êè. õîäå ýêñïåðèìåíòà, îñîáåííî åñëè îí ïðåäïîëàãàåò ñåðüåçíîå âìåøàòåëüñòâî â îðãàíèçì æèâîòíîãî, ôóíêöèîíàëüíûå ñèñòåìû æèâîòíûõ ìîãóò èçìåíèòüñÿ.