The 16 references with contexts in paper A. Khokhlov L., Yu. Rybachkova V., А. Хохлов Л., Ю. Рыбачкова В. (2018) “Генетическое тестирование в прогнозировании и течении хронической сердечной недостаточности на фоне артериальной гипертензии // Genetic testing for forecasting and course of the chronic heart failure against the background arterial hypertension” / spz:neicon:vedomostincesmp:y:2016:i:1:p:56-60

1
Atroschenko ES. Patients with chronic heart failure and preserved left ventricular systolic function. Serdechnaya nedostatochnost
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    ýôôåêòèâíîñòü è áåçîïàñíîñòü òåðàïèè, ñâîåâðåìåííî âûáðàòü íàèáîëåå ýôôåêòèâíîå ëåêàðñòâî â êà÷åñòâå ïåðâîî÷åðåäíîãî òåðàïåâòè÷åñêîãî ñðåäñòâà è âûÿâèòü çíà÷èìûå ãåíåòè÷åñêèå êðèòåðèè â ïðîãíîçèðîâàíèè òå÷åíèÿ õðîíè÷åñêîé ñåðäå÷íîé íåäîñòàòî÷íîñòè íà ôîíå àðòåðèàëüíîé ãèïåðòåíçèè. Íåóêëîííûé ðîñò ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, è ÕÑÍ â ÷àñòíîñòè, ñâèäåòåëüñòâóåò îá àêòóàëüíîñòè äàííîé òåìàòèêè
    Exact
    [1, 9, 8]
    Suffix
    . Ïî äàííûì îòäåëüíûõ èññëåäîâàíèé, ðàñïðîñòðàíåííîñòü ÕÑÍ ñîñòàâëÿåò îêîëî 2% è ñ êàæäûì ãîäîì íåóêëîííî âîçðàñòàåò. Ñîãëàñíî îòå÷åñòâåííûì èññëåäîâàíèÿì [7] â ñòàðøèõ âîçðàñòíûõ ãðóïïàõ ÷àñòîòà ÕÑÍ ñîñòàâëÿåò îêîëî 10%.

2
07; 8(6): 297–300 (in Russian). 2. Boytsov SA, Kirichenko PYu, Kuznetsov AE, et al. Study ID polymorphism of the angiotensin-converting enzyme A/C gene polymorphism in type I receptors of angiotensin II in patients with chronic heart failure of various functional classes, developed on the background of coronary artery disease. Serdechnaya nedostatochnost 2006; 4(2): 98–102 (in Russian).
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     íàñòîÿùåå âðåìÿ äîñòèæåíèÿ â êëèíè÷åñêîé ãåíåòèêå ñâÿçûâàþò ñ âûäåëåíèåì àëëåëåé (âàðèàíòîâ) ðàçëè÷íûõ ãåíîâ, îöåíêîé èõ ÷àñòîòû è îáíàðóæåíèåì ñâÿçåé îïðåäåëåííûõ àëëåëåé ñ ôåíîòèïè÷åñêèìè ïðîÿâëåíèÿìè, ñ ïîïûòêîé âûÿâëåíèÿ ïðîãíîñòè÷åñêèõ ïðèçíàêîâ. Ïîëó÷åíû äàííûå î ïîëèìîðôèçìå ãåíîâ ðÿäà ôàêòîðîâ, èãðàþùèõ ðîëü â ïàòîãåíåçå ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÑÍ)
    Exact
    [2, 11, 12]
    Suffix
    . Ïðåæäå âñåãî, ýòî ïîëèìîðôèçì ãåíîâ ôàêòîðîâ ðåíèí-àíãèîòåíçèí-àëüäîñòåðîíîâîé ñèñòåìû (ÐÀÀÑ). Ðîëü ÐÀÀÑ â ðàçâèòèè ñåðäå÷íî-ñîñóäèñòîãî ðåìîäåëèðîâàíèÿ õîðîøî èçâåñòíà [5, 10]. Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñê

3
Khokhlov AA, Yavorsky AN, Ignatiev VS, Sinitsyna OA, Stepanov IO, Voronina EA, Melnikova YuE. Culture of medication safety. Yaroslavl; 2011 (in Russian).
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    Âåäîìîñòè Íàó÷íîãî öåíòðà ýêñïåðòèçû ñðåäñòâ ìåäèöèíñêîãî ïðèìåíåíèÿ 2016; (1): 56–60. Ñîâðåìåííûå ïîäõîäû ê ëåêàðñòâåííîé òåðàïèè äîëæíû îïèðàòüñÿ íå òîëüêî íà ýôôåêòèâíîñòü, íî è íà âñåñòîðîííþþ îöåíêó áåçîïàñíîñòè ëåêàðñòâåííûõ ïðåïàðàòîâ
    Exact
    [3, 4]
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    .  êà÷åñòâå îäíîãî èç ïðîãíîñòè÷åñêèõ êðèòåðèåâ âûñîêîé ýôôåêòèâíîñòè è áåçîïàñíîñòè ôàðìàêîòåðàïèè ïðè õðîíè÷åñêîé ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÕÑÍ) ðàññìàòðèâàþòñÿ ãåíåòè÷åñêèå îñîáåííîñòè ïàöèåíòà.

4
Starodubov VI, Kagramanyan IN, eds. Health Technology Assessment. International experience. Moscow; 2012 (in Russian).
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    Âåäîìîñòè Íàó÷íîãî öåíòðà ýêñïåðòèçû ñðåäñòâ ìåäèöèíñêîãî ïðèìåíåíèÿ 2016; (1): 56–60. Ñîâðåìåííûå ïîäõîäû ê ëåêàðñòâåííîé òåðàïèè äîëæíû îïèðàòüñÿ íå òîëüêî íà ýôôåêòèâíîñòü, íî è íà âñåñòîðîííþþ îöåíêó áåçîïàñíîñòè ëåêàðñòâåííûõ ïðåïàðàòîâ
    Exact
    [3, 4]
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    .  êà÷åñòâå îäíîãî èç ïðîãíîñòè÷åñêèõ êðèòåðèåâ âûñîêîé ýôôåêòèâíîñòè è áåçîïàñíîñòè ôàðìàêîòåðàïèè ïðè õðîíè÷åñêîé ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÕÑÍ) ðàññìàòðèâàþòñÿ ãåíåòè÷åñêèå îñîáåííîñòè ïàöèåíòà.

5
Gorbunov VV, Kuzmin AG, Gorbunov EB, Kuzmina OM. Postinfarction remodeling of the left ventricle and the lack of polyunsaturated fatty acids. Serdechnaya nedostatochnost 2011; 12(4): 212–217 (in Russian).
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    Ïîëó÷åíû äàííûå î ïîëèìîðôèçìå ãåíîâ ðÿäà ôàêòîðîâ, èãðàþùèõ ðîëü â ïàòîãåíåçå ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÑÍ) [2, 11, 12]. Ïðåæäå âñåãî, ýòî ïîëèìîðôèçì ãåíîâ ôàêòîðîâ ðåíèí-àíãèîòåíçèí-àëüäîñòåðîíîâîé ñèñòåìû (ÐÀÀÑ). Ðîëü ÐÀÀÑ â ðàçâèòèè ñåðäå÷íî-ñîñóäèñòîãî ðåìîäåëèðîâàíèÿ õîðîøî èçâåñòíà
    Exact
    [5, 10]
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    . Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé [14, 16, 17].

6
Palova TV, Polyakov VP, Duplyakov DV, et al. Distribution of polymorphisms of genes of some components of the hemostatic system in patients with coronary heart disease. Kardiologiya 2009; (4): 9–13 (in Russian).
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    ÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé [14, 16, 17]. Îäíàêî, èìåþùèåñÿ â ëèòåðàòóðå äàííûå êëèíè÷åñêèõ èññëåäîâàíèé î ïîëèìîðôíûõ âàðèàíòàõ ãåíîâ, îòâåòñòâåííûõ çà ðàçâèòèå ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, ïðîòèâîðå÷èâû
    Exact
    [6, 12, 15]
    Suffix
    . Íå èçó÷åíà ïðîãíîñòè÷åñêàÿ öåííîñòü âûÿâëåííûõ ïîëèìîðôíûõ ìàðêåðîâ ãåíîâ ñòðóêòóðíûõ áåëêîâ ó áîëüíûõ àðòåðèàëüíîé ãèïåðòåíçèåé (ÀÃ), îòÿãîùåííîé ÕÑÍ. Âñå ýòî ñâèäåòåëüñòâóåò î òîì, ÷òî èññëåäîâàíèÿ â äàííîé îáëàñòè ÿâëÿþòñÿ âåñüìà àêòóàëüíûìè è ïåðñïåêòèâíûìè.

7
Ageev FT, Belenkov YuN, Fomin IV, et al. Prevalence of chronic heart failure in the European part of the Russian Federation — Data of EPOHA-SN. Serdechnaya nedostatochnost 2006; 7(1): 112–115 (in Russian).
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    Íåóêëîííûé ðîñò ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, è ÕÑÍ â ÷àñòíîñòè, ñâèäåòåëüñòâóåò îá àêòóàëüíîñòè äàííîé òåìàòèêè [1, 9, 8]. Ïî äàííûì îòäåëüíûõ èññëåäîâàíèé, ðàñïðîñòðàíåííîñòü ÕÑÍ ñîñòàâëÿåò îêîëî 2% è ñ êàæäûì ãîäîì íåóêëîííî âîçðàñòàåò. Ñîãëàñíî îòå÷åñòâåííûì èññëåäîâàíèÿì
    Exact
    [7]
    Suffix
    â ñòàðøèõ âîçðàñòíûõ ãðóïïàõ ÷àñòîòà ÕÑÍ ñîñòàâëÿåò îêîëî 10%.  íàñòîÿùåå âðåìÿ äîñòèæåíèÿ â êëèíè÷åñêîé ãåíåòèêå ñâÿçûâàþò ñ âûäåëåíèåì àëëåëåé (âàðèàíòîâ) ðàçëè÷íûõ ãåíîâ, îöåíêîé èõ ÷àñòîòû è îáíàðóæåíèåì ñâÿçåé îïðåäåëåííûõ àëëåëåé ñ ôåíîòèïè÷åñêèìè ïðîÿâëåíèÿìè, ñ ïîïûòêîé âûÿâëåíèÿ ïðîãíîñòè÷åñêèõ ïðèçíàêîâ.

8
Ageev FT, Arutyunov GP, Belenkov YuN. Chronic heart failure. Moscow: GEOTAR Media; 2010 (in Russian).
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    ýôôåêòèâíîñòü è áåçîïàñíîñòü òåðàïèè, ñâîåâðåìåííî âûáðàòü íàèáîëåå ýôôåêòèâíîå ëåêàðñòâî â êà÷åñòâå ïåðâîî÷åðåäíîãî òåðàïåâòè÷åñêîãî ñðåäñòâà è âûÿâèòü çíà÷èìûå ãåíåòè÷åñêèå êðèòåðèè â ïðîãíîçèðîâàíèè òå÷åíèÿ õðîíè÷åñêîé ñåðäå÷íîé íåäîñòàòî÷íîñòè íà ôîíå àðòåðèàëüíîé ãèïåðòåíçèè. Íåóêëîííûé ðîñò ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, è ÕÑÍ â ÷àñòíîñòè, ñâèäåòåëüñòâóåò îá àêòóàëüíîñòè äàííîé òåìàòèêè
    Exact
    [1, 9, 8]
    Suffix
    . Ïî äàííûì îòäåëüíûõ èññëåäîâàíèé, ðàñïðîñòðàíåííîñòü ÕÑÍ ñîñòàâëÿåò îêîëî 2% è ñ êàæäûì ãîäîì íåóêëîííî âîçðàñòàåò. Ñîãëàñíî îòå÷åñòâåííûì èññëåäîâàíèÿì [7] â ñòàðøèõ âîçðàñòíûõ ãðóïïàõ ÷àñòîòà ÕÑÍ ñîñòàâëÿåò îêîëî 10%.

9
Tereschenko SN, Uskach TM, Akimova OS, Kochetov AG. Chronic heart failure in clinical practice. Serdechnaya nedostatochnost 2004; 5(1): 9–11 (in Russian).
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    ýôôåêòèâíîñòü è áåçîïàñíîñòü òåðàïèè, ñâîåâðåìåííî âûáðàòü íàèáîëåå ýôôåêòèâíîå ëåêàðñòâî â êà÷åñòâå ïåðâîî÷åðåäíîãî òåðàïåâòè÷åñêîãî ñðåäñòâà è âûÿâèòü çíà÷èìûå ãåíåòè÷åñêèå êðèòåðèè â ïðîãíîçèðîâàíèè òå÷åíèÿ õðîíè÷åñêîé ñåðäå÷íîé íåäîñòàòî÷íîñòè íà ôîíå àðòåðèàëüíîé ãèïåðòåíçèè. Íåóêëîííûé ðîñò ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, è ÕÑÍ â ÷àñòíîñòè, ñâèäåòåëüñòâóåò îá àêòóàëüíîñòè äàííîé òåìàòèêè
    Exact
    [1, 9, 8]
    Suffix
    . Ïî äàííûì îòäåëüíûõ èññëåäîâàíèé, ðàñïðîñòðàíåííîñòü ÕÑÍ ñîñòàâëÿåò îêîëî 2% è ñ êàæäûì ãîäîì íåóêëîííî âîçðàñòàåò. Ñîãëàñíî îòå÷åñòâåííûì èññëåäîâàíèÿì [7] â ñòàðøèõ âîçðàñòíûõ ãðóïïàõ ÷àñòîòà ÕÑÍ ñîñòàâëÿåò îêîëî 10%.

10
Shlyakhto EV, Sitnikova MYu. Modern methods of prognosis in heart failure. Serdechnaya nedostatochnost 2009; 10(6): 322–334 (in Russian).
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    Ïîëó÷åíû äàííûå î ïîëèìîðôèçìå ãåíîâ ðÿäà ôàêòîðîâ, èãðàþùèõ ðîëü â ïàòîãåíåçå ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÑÍ) [2, 11, 12]. Ïðåæäå âñåãî, ýòî ïîëèìîðôèçì ãåíîâ ôàêòîðîâ ðåíèí-àíãèîòåíçèí-àëüäîñòåðîíîâîé ñèñòåìû (ÐÀÀÑ). Ðîëü ÐÀÀÑ â ðàçâèòèè ñåðäå÷íî-ñîñóäèñòîãî ðåìîäåëèðîâàíèÿ õîðîøî èçâåñòíà
    Exact
    [5, 10]
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    . Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé [14, 16, 17].

11
McNamara DM, Tarn SW, Sabolinski ML, et al. Aldosterone synthase promoter polymorphism predicts outcome in African Americans with heart failure: results from the A-HeFT Trial. J Am Coll Ñardiol. 2006; 48: 1277–1282.
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     íàñòîÿùåå âðåìÿ äîñòèæåíèÿ â êëèíè÷åñêîé ãåíåòèêå ñâÿçûâàþò ñ âûäåëåíèåì àëëåëåé (âàðèàíòîâ) ðàçëè÷íûõ ãåíîâ, îöåíêîé èõ ÷àñòîòû è îáíàðóæåíèåì ñâÿçåé îïðåäåëåííûõ àëëåëåé ñ ôåíîòèïè÷åñêèìè ïðîÿâëåíèÿìè, ñ ïîïûòêîé âûÿâëåíèÿ ïðîãíîñòè÷åñêèõ ïðèçíàêîâ. Ïîëó÷åíû äàííûå î ïîëèìîðôèçìå ãåíîâ ðÿäà ôàêòîðîâ, èãðàþùèõ ðîëü â ïàòîãåíåçå ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÑÍ)
    Exact
    [2, 11, 12]
    Suffix
    . Ïðåæäå âñåãî, ýòî ïîëèìîðôèçì ãåíîâ ôàêòîðîâ ðåíèí-àíãèîòåíçèí-àëüäîñòåðîíîâîé ñèñòåìû (ÐÀÀÑ). Ðîëü ÐÀÀÑ â ðàçâèòèè ñåðäå÷íî-ñîñóäèñòîãî ðåìîäåëèðîâàíèÿ õîðîøî èçâåñòíà [5, 10]. Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñê

12
Goldbergova M, Spinarova L, Spinar J, et al. Association of two angiotensinogen gene polymorphisms, M235T and G(-6)A, with chronic heart failure. Int J Cardiol. 2003; 89(2–3): 267–272.
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     íàñòîÿùåå âðåìÿ äîñòèæåíèÿ â êëèíè÷åñêîé ãåíåòèêå ñâÿçûâàþò ñ âûäåëåíèåì àëëåëåé (âàðèàíòîâ) ðàçëè÷íûõ ãåíîâ, îöåíêîé èõ ÷àñòîòû è îáíàðóæåíèåì ñâÿçåé îïðåäåëåííûõ àëëåëåé ñ ôåíîòèïè÷åñêèìè ïðîÿâëåíèÿìè, ñ ïîïûòêîé âûÿâëåíèÿ ïðîãíîñòè÷åñêèõ ïðèçíàêîâ. Ïîëó÷åíû äàííûå î ïîëèìîðôèçìå ãåíîâ ðÿäà ôàêòîðîâ, èãðàþùèõ ðîëü â ïàòîãåíåçå ñåðäå÷íîé íåäîñòàòî÷íîñòè (ÑÍ)
    Exact
    [2, 11, 12]
    Suffix
    . Ïðåæäå âñåãî, ýòî ïîëèìîðôèçì ãåíîâ ôàêòîðîâ ðåíèí-àíãèîòåíçèí-àëüäîñòåðîíîâîé ñèñòåìû (ÐÀÀÑ). Ðîëü ÐÀÀÑ â ðàçâèòèè ñåðäå÷íî-ñîñóäèñòîãî ðåìîäåëèðîâàíèÿ õîðîøî èçâåñòíà [5, 10]. Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñê

  2. In-text reference with the coordinate start=3658
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    ÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé [14, 16, 17]. Îäíàêî, èìåþùèåñÿ â ëèòåðàòóðå äàííûå êëèíè÷åñêèõ èññëåäîâàíèé î ïîëèìîðôíûõ âàðèàíòàõ ãåíîâ, îòâåòñòâåííûõ çà ðàçâèòèå ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, ïðîòèâîðå÷èâû
    Exact
    [6, 12, 15]
    Suffix
    . Íå èçó÷åíà ïðîãíîñòè÷åñêàÿ öåííîñòü âûÿâëåííûõ ïîëèìîðôíûõ ìàðêåðîâ ãåíîâ ñòðóêòóðíûõ áåëêîâ ó áîëüíûõ àðòåðèàëüíîé ãèïåðòåíçèåé (ÀÃ), îòÿãîùåííîé ÕÑÍ. Âñå ýòî ñâèäåòåëüñòâóåò î òîì, ÷òî èññëåäîâàíèÿ â äàííîé îáëàñòè ÿâëÿþòñÿ âåñüìà àêòóàëüíûìè è ïåðñïåêòèâíûìè.

14
Fiuzat M, Bristow MR. Pharmacogenetics in heart failure trials. Heart Fail Clin. 2011;7(4): 553–559.
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    Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé
    Exact
    [14, 16, 17]
    Suffix
    . Îäíàêî, èìåþùèåñÿ â ëèòåðàòóðå äàííûå êëèíè÷åñêèõ èññëåäîâàíèé î ïîëèìîðôíûõ âàðèàíòàõ ãåíîâ, îòâåòñòâåííûõ çà ðàçâèòèå ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, ïðîòèâîðå÷èâû [6, 12, 15]. Íå èçó÷åíà ïðîãíîñòè÷åñêàÿ öåííîñòü âûÿâëåííûõ ïîëèìîðôíûõ ìàðêåðîâ ãåíîâ ñòðóêòóðíûõ áåëêîâ ó áîëüíûõ àðòåðèàëüíîé ãèïåðòåíçèåé (ÀÃ), îòÿãîùåííîé ÕÑÍ.

15
Holmen OL, Romundstad S, Melien O. Association between the G proteinb3 subunit C825T polymorphism and the occurrence of cardiovascular disease in hypertensives: The Nord-Trøndelag Health Study (HUNT). Am J Hypertens. 2010; 23(10): 1121–1127.
Total in-text references: 1
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    ÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé [14, 16, 17]. Îäíàêî, èìåþùèåñÿ â ëèòåðàòóðå äàííûå êëèíè÷åñêèõ èññëåäîâàíèé î ïîëèìîðôíûõ âàðèàíòàõ ãåíîâ, îòâåòñòâåííûõ çà ðàçâèòèå ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, ïðîòèâîðå÷èâû
    Exact
    [6, 12, 15]
    Suffix
    . Íå èçó÷åíà ïðîãíîñòè÷åñêàÿ öåííîñòü âûÿâëåííûõ ïîëèìîðôíûõ ìàðêåðîâ ãåíîâ ñòðóêòóðíûõ áåëêîâ ó áîëüíûõ àðòåðèàëüíîé ãèïåðòåíçèåé (ÀÃ), îòÿãîùåííîé ÕÑÍ. Âñå ýòî ñâèäåòåëüñòâóåò î òîì, ÷òî èññëåäîâàíèÿ â äàííîé îáëàñòè ÿâëÿþòñÿ âåñüìà àêòóàëüíûìè è ïåðñïåêòèâíûìè.

16
Parsa A, Chang YP, Kelly RJ, Corretti MC, et al. Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality. Clin Transl Sci. 2011; 4(1): 17–23.
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    Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé
    Exact
    [14, 16, 17]
    Suffix
    . Îäíàêî, èìåþùèåñÿ â ëèòåðàòóðå äàííûå êëèíè÷åñêèõ èññëåäîâàíèé î ïîëèìîðôíûõ âàðèàíòàõ ãåíîâ, îòâåòñòâåííûõ çà ðàçâèòèå ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, ïðîòèâîðå÷èâû [6, 12, 15]. Íå èçó÷åíà ïðîãíîñòè÷åñêàÿ öåííîñòü âûÿâëåííûõ ïîëèìîðôíûõ ìàðêåðîâ ãåíîâ ñòðóêòóðíûõ áåëêîâ ó áîëüíûõ àðòåðèàëüíîé ãèïåðòåíçèåé (ÀÃ), îòÿãîùåííîé ÕÑÍ.

17
Mant J, Doust J, Roalfe A, et al. Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of implications of different diagnostic strategies in primary care. Health Technol Assess. 2009; 13(32): 1–207. AUTHORS
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    Îïðåäåëåíèå ãåíåòè÷åñêèõ ìàðêåðîâ â êàðäèîëîãèè ïîäâåðãàåòñÿ èíòåíñèâíîìó èçó÷åíèþ è èññëåäîâàíèþ ñ öåëüþ âûÿâëåíèÿ ãåíåòè÷åñêîãî ðèñêà è íà îñíîâå ýòîãî ïðîãíîçèðîâàíèÿ îñëîæíåíèé çàáîëåâàíèÿ äî ïîÿâëåíèÿ êëèíè÷åñêèõ ïðîÿâëåíèé
    Exact
    [14, 16, 17]
    Suffix
    . Îäíàêî, èìåþùèåñÿ â ëèòåðàòóðå äàííûå êëèíè÷åñêèõ èññëåäîâàíèé î ïîëèìîðôíûõ âàðèàíòàõ ãåíîâ, îòâåòñòâåííûõ çà ðàçâèòèå ñåðäå÷íî-ñîñóäèñòûõ çàáîëåâàíèé, ïðîòèâîðå÷èâû [6, 12, 15]. Íå èçó÷åíà ïðîãíîñòè÷åñêàÿ öåííîñòü âûÿâëåííûõ ïîëèìîðôíûõ ìàðêåðîâ ãåíîâ ñòðóêòóðíûõ áåëêîâ ó áîëüíûõ àðòåðèàëüíîé ãèïåðòåíçèåé (ÀÃ), îòÿãîùåííîé ÕÑÍ.