The 27 references with contexts in paper Z. UNAROKOV M., T. MUKHOEDOVA V., O. SHUVAEVA V., З. УНАРОКОВ М., Т. МУХОЕДОВА В., О. ШУВАЕВА В. (2011) “ДИНАМИКА АЦЕТАТЕМИИ ПРИ ПРИМЕНЕНИИ БИКАРБОНАТНОГО И БЕЗАЦЕТАТНОГО ДИАЛИЗАТА У БОЛЬНЫХ С ОСТРЫМ ПОЧЕЧНЫМ ПОВРЕЖДЕНИЕМ // THE DYNAMICS OF ACETATEMIA WITH USING BICARBONATE AND ACETATE-FREE DIALYSATE IN PATIENTS WITH ACUTE KIDNEY INJURY” / spz:neicon:nefr:y:2011:i:4:p:34-38

1
Kumar VA, Craig M, Depner T, Yeun JY. Extended daily dialysis: A new approach to renal replacement for acute renal failure in the intensive care unit. Am J Kidney Dis 2000; 36: 294 –300
Total in-text references: 1
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    ãåìîäèàëèç (ÃÄ) èëè ãåìîäèàôèëüòðàöèþ (ÃÄÔ), êîòîðûå ïðîâîäÿòñÿ íà îáû÷íîé äèàëèçíîé àïïàðàòóðå â âèäå åæåäíåâíûõ ñåàíñîâ, íî áîëåå äëèòåëüíûõ, è â ìåíåå èíòåíñèâíîì ðåæèìå, ÷åì òðàäèöèîííûé èíòåðìèòòèðóþùèé ÃÄ. Ê èõ äîñòîèíñòâàì îòíîñÿòñÿ íåâûñîêèå ýêîíîìè÷åñêèå è îðãàíèçàöèîííûå çàòðàòû, ïî ñðàâíåíèþ ñ ÏÇÏÒ, è ìåíüøèé ðèñê ãåìîäèíàìè÷åñêèõ îñëîæíåíèé, ïî ñðàâíåíèþ ñ òðàäèöèîííîé ÈÇÏÒ
    Exact
    [1–3]
    Suffix
    .  öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ [4–6].

2
Tonelli M, Manns B, Feller-Kopman D. Acute renal failure in the intensive care unit: a systematic review of the impact of dialytic modality on mortality and renal recovery. Am J Kidney Dis 2002; 40: 875–885
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    Prefix
    ãåìîäèàëèç (ÃÄ) èëè ãåìîäèàôèëüòðàöèþ (ÃÄÔ), êîòîðûå ïðîâîäÿòñÿ íà îáû÷íîé äèàëèçíîé àïïàðàòóðå â âèäå åæåäíåâíûõ ñåàíñîâ, íî áîëåå äëèòåëüíûõ, è â ìåíåå èíòåíñèâíîì ðåæèìå, ÷åì òðàäèöèîííûé èíòåðìèòòèðóþùèé ÃÄ. Ê èõ äîñòîèíñòâàì îòíîñÿòñÿ íåâûñîêèå ýêîíîìè÷åñêèå è îðãàíèçàöèîííûå çàòðàòû, ïî ñðàâíåíèþ ñ ÏÇÏÒ, è ìåíüøèé ðèñê ãåìîäèíàìè÷åñêèõ îñëîæíåíèé, ïî ñðàâíåíèþ ñ òðàäèöèîííîé ÈÇÏÒ
    Exact
    [1–3]
    Suffix
    .  öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ [4–6].

3
Marshall M.R, Ma T, Galler D et al. Sustained lowefficiency daily diafiltration (SLEDD-f) for critically ill patients requiring renal replacement therapy: towards an adequate therapy. Nephrol Dial Transplant 2004; V. 19: 877-884
Total in-text references: 1
  1. In-text reference with the coordinate start=5030
    Prefix
    ãåìîäèàëèç (ÃÄ) èëè ãåìîäèàôèëüòðàöèþ (ÃÄÔ), êîòîðûå ïðîâîäÿòñÿ íà îáû÷íîé äèàëèçíîé àïïàðàòóðå â âèäå åæåäíåâíûõ ñåàíñîâ, íî áîëåå äëèòåëüíûõ, è â ìåíåå èíòåíñèâíîì ðåæèìå, ÷åì òðàäèöèîííûé èíòåðìèòòèðóþùèé ÃÄ. Ê èõ äîñòîèíñòâàì îòíîñÿòñÿ íåâûñîêèå ýêîíîìè÷åñêèå è îðãàíèçàöèîííûå çàòðàòû, ïî ñðàâíåíèþ ñ ÏÇÏÒ, è ìåíüøèé ðèñê ãåìîäèíàìè÷åñêèõ îñëîæíåíèé, ïî ñðàâíåíèþ ñ òðàäèöèîííîé ÈÇÏÒ
    Exact
    [1–3]
    Suffix
    .  öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ [4–6].

4
Lonnemann G, Floege J, Kliem V et al. Extended daily veno-venous high flux haemodialysis in patients with acute renal failure and multiple organ dysfunction syndrome using a single path batch dialysis system. Nephrol Dial Transplant 2000; 15: 1189–1193
Total in-text references: 1
  1. In-text reference with the coordinate start=5235
    Prefix
     öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ
    Exact
    [4–6]
    Suffix
    .  òî æå âðåìÿ, íåò êîíñåíñóñà â îòíîøåíèè ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè ïðè SLEDD. Òàê, ïî ìíåíèþ R. Bellomo è ñîàâò. [7], «SLED ñëåäóåò ïðèìåíÿòü ñ áîëüøîé îñòîðîæíîñòüþ èëè âîîáùå íå ïðèìåíÿòü ó ðÿäà áîëüíûõ â ãèïåðîñòðîì ñîñòîÿíèè», à C.

5
Kielstein JT, Kretschmer U, Ernst T et al. Efficacy and cardiovascular tolerability of extended dialysis in critically ill patients: a randomized controlled study. Am J Kidney Dis 2004; 43(2):342-349.
Total in-text references: 1
  1. In-text reference with the coordinate start=5235
    Prefix
     öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ
    Exact
    [4–6]
    Suffix
    .  òî æå âðåìÿ, íåò êîíñåíñóñà â îòíîøåíèè ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè ïðè SLEDD. Òàê, ïî ìíåíèþ R. Bellomo è ñîàâò. [7], «SLED ñëåäóåò ïðèìåíÿòü ñ áîëüøîé îñòîðîæíîñòüþ èëè âîîáùå íå ïðèìåíÿòü ó ðÿäà áîëüíûõ â ãèïåðîñòðîì ñîñòîÿíèè», à C.

6
Kumar VA, Yeun JY, Depner TA, Don BR . Extended daily dialysis vs. continuous hemodialysis for ICU patients with acute renal failure. Int J Artif Organs 2004; 27(5): 371–379
Total in-text references: 1
  1. In-text reference with the coordinate start=5235
    Prefix
     öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ
    Exact
    [4–6]
    Suffix
    .  òî æå âðåìÿ, íåò êîíñåíñóñà â îòíîøåíèè ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè ïðè SLEDD. Òàê, ïî ìíåíèþ R. Bellomo è ñîàâò. [7], «SLED ñëåäóåò ïðèìåíÿòü ñ áîëüøîé îñòîðîæíîñòüþ èëè âîîáùå íå ïðèìåíÿòü ó ðÿäà áîëüíûõ â ãèïåðîñòðîì ñîñòîÿíèè», à C.

7
Bellomo R, Baldwin I, Naka T et al. Длительная интермиттирующая почечно-заместительная терапия в отделении реанимации. Анестезиология и реаниматология 2005; (2):74-78
Total in-text references: 1
  1. In-text reference with the coordinate start=5359
    Prefix
     öåëîì, SLEDD øèðîêî ïðèìåíÿåòñÿ â ëå÷åíèè òÿæåëîãî ÎÏÏ ó áîëüíûõ ñî ñíèæåííîé òîëåðàíòíîñòüþ ê èíòåðìèòòèðóþùåé òåðàïèè è â ëèòåðàòóðå ïîñëåäíèõ ëåò ðàññìàòðèâàåòñÿ êàê âîçìîæíàÿ àëüòåðíàòèâà ÏÇÏÒ [4–6].  òî æå âðåìÿ, íåò êîíñåíñóñà â îòíîøåíèè ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè ïðè SLEDD. Òàê, ïî ìíåíèþ R. Bellomo è ñîàâò.
    Exact
    [7]
    Suffix
    , «SLED ñëåäóåò ïðèìåíÿòü ñ áîëüøîé îñòîðîæíîñòüþ èëè âîîáùå íå ïðèìåíÿòü ó ðÿäà áîëüíûõ â ãèïåðîñòðîì ñîñòîÿíèè», à C. Ronco è ñîàâò. [8] ñ÷èòàþò áîëåå öåëåñîîáðàçíûì «ïðèìåíÿòü â ãèïåðîñòðîì ñîñòîÿíèè ÏÇÏÒ, à ïîñëå ñòàáèëèçàöèè ñîñòîÿíèÿ SLED».

8
Ricci Z, Ronco C. Dose and efficiency of renal replacement therapy: Continuous renal replacement therapy versus intermittent hemodialysis versus slow extended daily dialysis. Crit Care Med 2008; 36 (Suppl 4): S229-S237
Total in-text references: 1
  1. In-text reference with the coordinate start=5497
    Prefix
     òî æå âðåìÿ, íåò êîíñåíñóñà â îòíîøåíèè ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè ïðè SLEDD. Òàê, ïî ìíåíèþ R. Bellomo è ñîàâò. [7], «SLED ñëåäóåò ïðèìåíÿòü ñ áîëüøîé îñòîðîæíîñòüþ èëè âîîáùå íå ïðèìåíÿòü ó ðÿäà áîëüíûõ â ãèïåðîñòðîì ñîñòîÿíèè», à C. Ronco è ñîàâò.
    Exact
    [8]
    Suffix
    ñ÷èòàþò áîëåå öåëåñîîáðàçíûì «ïðèìåíÿòü â ãèïåðîñòðîì ñîñòîÿíèè ÏÇÏÒ, à ïîñëå ñòàáèëèçàöèè ñîñòîÿíèÿ SLED». Îäíîé èç ïðè÷èí èíòðàäèàëèçíîé ñåðäå÷íîñîñóäèñòîé íåñòàáèëüíîñòè ìîæåò ÿâëÿòüñÿ àöåòàò, ñîäåðæàùèéñÿ â ñòàíäàðòíîì áèêàðáîíàòíîì äèàëèçèðóþùåì ðàñòâîðå êàê pH-ñòàáèëèçèðóþùèé ôàêòîð.

9
Fournier G, Potier J, Thebaud H-E et al. Substitution of acetic acid for hydrcloric acid in the bicarbonate buffered dialysate. Intern Soc for Artifical Org 1998; 22(7): 608-613
Total in-text references: 3
  1. In-text reference with the coordinate start=6525
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    Ïðè ýòîì ïîêàçàíà ÷åòêàÿ ñâÿçü ìåæäó êóìóëÿöèåé àöåòàòà â êðîâè è ãåìîäèíàìè÷åñêèìè îñëîæíåíèÿìè. Ïðèìåíåíèå ïîëíîñòüþ áåçàöåòàòíîãî äèàëèçàòà (ãäå àöåòàò çàìåíåí ðàñòâîðîì ñîëÿíîé êèñëîòû) ëèáî áåçàöåòàòíîé áèîôèëüòðàöèè ïîçâîëÿëî ñíèçèòü ÷àñòîòó îñëîæíåíèé ó ýòèõ áîëüíûõ
    Exact
    [9–12]
    Suffix
    . Îäíàêî äàííûå èññëåäîâàíèÿ êàñàþòñÿ áîëüíûõ ñ òåðìèíàëüíîé ÕÏÍ íà ðåãóëÿðíîì ÃÄ. Èññëåäîâàíèé äèíàìèêè àöåòàòåìèè ó áîëüíûõ ñ ÎÏÏ âî âðåìÿ SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì, êîãäà èñïîëüçóþòñÿ íåâûñîêèé êðîâîòîê è ïîòîê äèàëèçàòà, ò.å. «àöåòàòíàÿ íàãðóçêà», çíà÷èòåëüíî ìåíüøå, â äîñòóïíîé ëèòåðàòóðå íå íàéäåíî.

  2. In-text reference with the coordinate start=13347
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    Áîëåå ïîçäíèå èññëåäîâàíèÿ ïîêàçàëè, ÷òî ìàêñèìàëüíûé ðîñò àöåòàòà â êðîâè âî âðåìÿ áèêàðáîíàòíîãî äèàëèçà îòìå÷àëñÿ ó áîëüíûõ ñ èñõîäíîé àöåòàòåìèåé.  òî æå âðåìÿ, âî âðåìÿ áåçàöåòàòíîãî äèàëèçà èñõîäíî âûñîêèé óðîâåíü àöåòàòà èìåë òåíäåíöèþ ê íîðìàëèçàöèè
    Exact
    [9, 12]
    Suffix
    .  ïîñëåäíèå ãîäû óòî÷íåíû ïðÿìûå è îïîñðåäîâàííûå ìåõàíèçìû êàðäèîäåïðåññèâíîãî äåéñòâèÿ àöåòàòà. Íåïîñðåäñòâåííûìè ìåõàíèçìàìè ñ÷èòàþòñÿ èíäóêöèÿ ãèïîêñèè ñ ïîñëåäóþùåé àêòèâàöèåé ïðîâîñïàëèòåëüíîãî öèòîêèíîâîãî êàñêàäà, àêòèâàöèÿ öèêëîîêñèãåíàçû è ëèïîîêñèãåíàçû, ñèíòåç ïðîñòàãëàíäèíîâ è òðîìáîêñàíà [11, 14,16].

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    Ïîâûøåíèå óðîâíÿ àöåòàòà â 4–5 ðàç îò èñõîäíîãî (èëè â 12–13 ðàç îò íîðìû) è ðàíã êîëåáàíèé (ìàêñèìàëüíî äî 2,1 ììîëü/ë) ïðè èñïîëüçîâàíèè áèêàðáîíàòíîãî äèàëèçàòà òàêæå ñîãëàñóþòñÿ ñ ëèòåðàòóðíûìè äàííûìè
    Exact
    [9, 12, 15]
    Suffix
    . Ñëåäóåò îòäåëüíî îòìåòèòü, ÷òî â íàøåì èññëåäîâàíèè ó áîëüøèíñòâà áîëüíûõ èìåëèñü îäíîâðåìåííî íåñêîëüêî ôàêòîðîâ, âëèÿþùèõ íà ñêîðîñòü ìåòàáîëèçìà àöåòàòà. Îöåíêà ýôôåêòèâíîñòè êîððåêöèè ñàìîé ïî÷å÷íîé íåäîñòàòî÷íîñòè ïîêàçàëà îòñóòñòâèå çíà÷èìûõ ìåæãðóïïîâûõ ðàçëè÷èé.

10
Ding F, Ahrenholz P, Winkler RE et al. Online hemodiafiltration versus acetate-free biofiltration: a prospective crossover study. Artif Organs 2002; 26(2):169-180
Total in-text references: 1
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    Ïðè ýòîì ïîêàçàíà ÷åòêàÿ ñâÿçü ìåæäó êóìóëÿöèåé àöåòàòà â êðîâè è ãåìîäèíàìè÷åñêèìè îñëîæíåíèÿìè. Ïðèìåíåíèå ïîëíîñòüþ áåçàöåòàòíîãî äèàëèçàòà (ãäå àöåòàò çàìåíåí ðàñòâîðîì ñîëÿíîé êèñëîòû) ëèáî áåçàöåòàòíîé áèîôèëüòðàöèè ïîçâîëÿëî ñíèçèòü ÷àñòîòó îñëîæíåíèé ó ýòèõ áîëüíûõ
    Exact
    [9–12]
    Suffix
    . Îäíàêî äàííûå èññëåäîâàíèÿ êàñàþòñÿ áîëüíûõ ñ òåðìèíàëüíîé ÕÏÍ íà ðåãóëÿðíîì ÃÄ. Èññëåäîâàíèé äèíàìèêè àöåòàòåìèè ó áîëüíûõ ñ ÎÏÏ âî âðåìÿ SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì, êîãäà èñïîëüçóþòñÿ íåâûñîêèé êðîâîòîê è ïîòîê äèàëèçàòà, ò.å. «àöåòàòíàÿ íàãðóçêà», çíà÷èòåëüíî ìåíüøå, â äîñòóïíîé ëèòåðàòóðå íå íàéäåíî.

11
Pizzarelli F, Cerrai T, Dattolo P et al. On-line haemdiafiltration with and without acetate. Nephrol Dial Transplant 2006; 21(6): 1648-1651
Total in-text references: 4
  1. In-text reference with the coordinate start=6525
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    Ïðè ýòîì ïîêàçàíà ÷åòêàÿ ñâÿçü ìåæäó êóìóëÿöèåé àöåòàòà â êðîâè è ãåìîäèíàìè÷åñêèìè îñëîæíåíèÿìè. Ïðèìåíåíèå ïîëíîñòüþ áåçàöåòàòíîãî äèàëèçàòà (ãäå àöåòàò çàìåíåí ðàñòâîðîì ñîëÿíîé êèñëîòû) ëèáî áåçàöåòàòíîé áèîôèëüòðàöèè ïîçâîëÿëî ñíèçèòü ÷àñòîòó îñëîæíåíèé ó ýòèõ áîëüíûõ
    Exact
    [9–12]
    Suffix
    . Îäíàêî äàííûå èññëåäîâàíèÿ êàñàþòñÿ áîëüíûõ ñ òåðìèíàëüíîé ÕÏÍ íà ðåãóëÿðíîì ÃÄ. Èññëåäîâàíèé äèíàìèêè àöåòàòåìèè ó áîëüíûõ ñ ÎÏÏ âî âðåìÿ SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì, êîãäà èñïîëüçóþòñÿ íåâûñîêèé êðîâîòîê è ïîòîê äèàëèçàòà, ò.å. «àöåòàòíàÿ íàãðóçêà», çíà÷èòåëüíî ìåíüøå, â äîñòóïíîé ëèòåðàòóðå íå íàéäåíî.

  2. In-text reference with the coordinate start=13660
    Prefix
    Íåïîñðåäñòâåííûìè ìåõàíèçìàìè ñ÷èòàþòñÿ èíäóêöèÿ ãèïîêñèè ñ ïîñëåäóþùåé àêòèâàöèåé ïðîâîñïàëèòåëüíîãî öèòîêèíîâîãî êàñêàäà, àêòèâàöèÿ öèêëîîêñèãåíàçû è ëèïîîêñèãåíàçû, ñèíòåç ïðîñòàãëàíäèíîâ è òðîìáîêñàíà
    Exact
    [11, 14,16]
    Suffix
    . Êðîìå òîãî, àöåòàò àêòèâèçèðóåò ìàññèâíîå âûñâîáîæäåíèå îêñèäà àçîòà (NO) ïîñðåäñòâîì ñòèìóëÿöèè ñèíòåçà èíäóöèáåëüíîé NO-ñèíòåòàçû, ÷òî âûçûâàåò ñíèæåíèå ïåðèôåðè÷åñêîãî ñîñóäèñòîãî ñîïðîòèâëåíèÿ [11, 17].

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    Prefix
    Êðîìå òîãî, àöåòàò àêòèâèçèðóåò ìàññèâíîå âûñâîáîæäåíèå îêñèäà àçîòà (NO) ïîñðåäñòâîì ñòèìóëÿöèè ñèíòåçà èíäóöèáåëüíîé NO-ñèíòåòàçû, ÷òî âûçûâàåò ñíèæåíèå ïåðèôåðè÷åñêîãî ñîñóäèñòîãî ñîïðîòèâëåíèÿ
    Exact
    [11, 17]
    Suffix
    . Êëèíè÷åñêèì ïðîÿâëåíèåì ãåìîäèíàìè÷åñêèõ ýôôåêòîâ àöåòàòà ÿâëÿåòñÿ ñíèæåíèå ñèñòîëè÷åñêîãî è äèàñòîëè÷åñêîãî àðòåðèàëüíîãî äàâëåíèÿ â ñî÷åòàíèè ñ óâåëè÷åíèåì ÷àñòîòû ñåðäå÷íûõ ñîêðàùåíèé. Àíàëèç ðåçóëüòàòîâ íàøåãî èññëåäîâàíèÿ ïîêàçàë, ÷òî íàèáîëåå çíà÷èìûé ðîñò óðîâíÿ àöåòàòà ïîñëå SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì ðåãèñòðèðîâàëñÿ ó áîëüíûõ ñ îñòðîé ñåðäå÷íîé íåäîñòàòî÷íîñòüþ, íóæäàþùèõñÿ â èíîò

  4. In-text reference with the coordinate start=15427
    Prefix
    Ïðè ýòîì â ãðóïïå, ïîëó÷àâøåé SLEDD ñ áåçàöåòàòíûì äèàëèçàòîì, èñïîëüçîâàëàñü èñõîäíàÿ êîíöåíòðàöèÿ áèêàðáîíàòà, â ñðåäíåì íà 3 ììîëü/ë âûøå, ÷åì ïðè SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì, êàê ðåêîìåíäóåòñÿ â ðÿäå èññëåäîâàíèé, òàê êàê 3 ììîëü/ë ñîëÿíîé êèñëîòû, ñîäåðæàùåéñÿ â áåçàöåòàòíîì äèàëèçàòå, ñâÿçûâàþò 3 ììîëü/ë áèêàðáîíàòà
    Exact
    [11, 12]
    Suffix
    . Òàêèì îáðàçîì, íàøå èññëåäîâàíèå ïðîäåìîíñòðèðîâàëî, ÷òî çàìåíà àöåòàòà íà ñîëÿíóþ êèñëîòó â äèàëèçèðóþùåì ðàñòâîðå íå ïðèâîäèëà ê íåïîëíîöåííîé êîððåêöèè àöèäîçà è àçîòåìèè. Íî ïðè ýòîì ïðèìåíåíèå ïîëíîñòüþ áåçàöåòàòíîãî äèàëèçàòà ñïîñîáñòâîâàëî ñòàòèñòè÷åñêè çíà÷èìîìó ñíèæåíèþ ÷àñòîòû èíòðàäèàëèçíûõ ãèïîòåíçèé.

12
Coll E, Perez-Garcia R, Martin de Francisco AL et al. Acetate-free on-line PHF: how to improve hyperacetatemia and haemodynamic tolerance. Nefrologia 2009; 29(2):156-162
Total in-text references: 4
  1. In-text reference with the coordinate start=6525
    Prefix
    Ïðè ýòîì ïîêàçàíà ÷åòêàÿ ñâÿçü ìåæäó êóìóëÿöèåé àöåòàòà â êðîâè è ãåìîäèíàìè÷åñêèìè îñëîæíåíèÿìè. Ïðèìåíåíèå ïîëíîñòüþ áåçàöåòàòíîãî äèàëèçàòà (ãäå àöåòàò çàìåíåí ðàñòâîðîì ñîëÿíîé êèñëîòû) ëèáî áåçàöåòàòíîé áèîôèëüòðàöèè ïîçâîëÿëî ñíèçèòü ÷àñòîòó îñëîæíåíèé ó ýòèõ áîëüíûõ
    Exact
    [9–12]
    Suffix
    . Îäíàêî äàííûå èññëåäîâàíèÿ êàñàþòñÿ áîëüíûõ ñ òåðìèíàëüíîé ÕÏÍ íà ðåãóëÿðíîì ÃÄ. Èññëåäîâàíèé äèíàìèêè àöåòàòåìèè ó áîëüíûõ ñ ÎÏÏ âî âðåìÿ SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì, êîãäà èñïîëüçóþòñÿ íåâûñîêèé êðîâîòîê è ïîòîê äèàëèçàòà, ò.å. «àöåòàòíàÿ íàãðóçêà», çíà÷èòåëüíî ìåíüøå, â äîñòóïíîé ëèòåðàòóðå íå íàéäåíî.

  2. In-text reference with the coordinate start=13347
    Prefix
    Áîëåå ïîçäíèå èññëåäîâàíèÿ ïîêàçàëè, ÷òî ìàêñèìàëüíûé ðîñò àöåòàòà â êðîâè âî âðåìÿ áèêàðáîíàòíîãî äèàëèçà îòìå÷àëñÿ ó áîëüíûõ ñ èñõîäíîé àöåòàòåìèåé.  òî æå âðåìÿ, âî âðåìÿ áåçàöåòàòíîãî äèàëèçà èñõîäíî âûñîêèé óðîâåíü àöåòàòà èìåë òåíäåíöèþ ê íîðìàëèçàöèè
    Exact
    [9, 12]
    Suffix
    .  ïîñëåäíèå ãîäû óòî÷íåíû ïðÿìûå è îïîñðåäîâàííûå ìåõàíèçìû êàðäèîäåïðåññèâíîãî äåéñòâèÿ àöåòàòà. Íåïîñðåäñòâåííûìè ìåõàíèçìàìè ñ÷èòàþòñÿ èíäóêöèÿ ãèïîêñèè ñ ïîñëåäóþùåé àêòèâàöèåé ïðîâîñïàëèòåëüíîãî öèòîêèíîâîãî êàñêàäà, àêòèâàöèÿ öèêëîîêñèãåíàçû è ëèïîîêñèãåíàçû, ñèíòåç ïðîñòàãëàíäèíîâ è òðîìáîêñàíà [11, 14,16].

  3. In-text reference with the coordinate start=14586
    Prefix
    Ïîâûøåíèå óðîâíÿ àöåòàòà â 4–5 ðàç îò èñõîäíîãî (èëè â 12–13 ðàç îò íîðìû) è ðàíã êîëåáàíèé (ìàêñèìàëüíî äî 2,1 ììîëü/ë) ïðè èñïîëüçîâàíèè áèêàðáîíàòíîãî äèàëèçàòà òàêæå ñîãëàñóþòñÿ ñ ëèòåðàòóðíûìè äàííûìè
    Exact
    [9, 12, 15]
    Suffix
    . Ñëåäóåò îòäåëüíî îòìåòèòü, ÷òî â íàøåì èññëåäîâàíèè ó áîëüøèíñòâà áîëüíûõ èìåëèñü îäíîâðåìåííî íåñêîëüêî ôàêòîðîâ, âëèÿþùèõ íà ñêîðîñòü ìåòàáîëèçìà àöåòàòà. Îöåíêà ýôôåêòèâíîñòè êîððåêöèè ñàìîé ïî÷å÷íîé íåäîñòàòî÷íîñòè ïîêàçàëà îòñóòñòâèå çíà÷èìûõ ìåæãðóïïîâûõ ðàçëè÷èé.

  4. In-text reference with the coordinate start=15427
    Prefix
    Ïðè ýòîì â ãðóïïå, ïîëó÷àâøåé SLEDD ñ áåçàöåòàòíûì äèàëèçàòîì, èñïîëüçîâàëàñü èñõîäíàÿ êîíöåíòðàöèÿ áèêàðáîíàòà, â ñðåäíåì íà 3 ììîëü/ë âûøå, ÷åì ïðè SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì, êàê ðåêîìåíäóåòñÿ â ðÿäå èññëåäîâàíèé, òàê êàê 3 ììîëü/ë ñîëÿíîé êèñëîòû, ñîäåðæàùåéñÿ â áåçàöåòàòíîì äèàëèçàòå, ñâÿçûâàþò 3 ììîëü/ë áèêàðáîíàòà
    Exact
    [11, 12]
    Suffix
    . Òàêèì îáðàçîì, íàøå èññëåäîâàíèå ïðîäåìîíñòðèðîâàëî, ÷òî çàìåíà àöåòàòà íà ñîëÿíóþ êèñëîòó â äèàëèçèðóþùåì ðàñòâîðå íå ïðèâîäèëà ê íåïîëíîöåííîé êîððåêöèè àöèäîçà è àçîòåìèè. Íî ïðè ýòîì ïðèìåíåíèå ïîëíîñòüþ áåçàöåòàòíîãî äèàëèçàòà ñïîñîáñòâîâàëî ñòàòèñòè÷åñêè çíà÷èìîìó ñíèæåíèþ ÷àñòîòû èíòðàäèàëèçíûõ ãèïîòåíçèé.

13
Kirkendol PL, Devia CJ, Bower JD, Holbert RD. A comparison of the cardiovascular effects of sodium acetate, sodium bicarbonate and other potential sources of fixed base in hemodialysate solutions. Trans Am Soc Artif Intern Organs 1977; 23: 399-405
Total in-text references: 1
  1. In-text reference with the coordinate start=13076
    Prefix
    ±68141±46 Na, ммоль/л135,2±4,9136,±3,6132±6135±3 HCO3, ммоль/л24,2±2,825,9±3,926,1±1,826±2,2 Cl, ммоль/л102±4104±3101±7105±6 Лактат, ммоль/л2,1±0,91,9±1,22,2±1,22,4±1,4 àöåòàòà ìîãóò ñïîñîáñòâîâàòü ðàçëè÷íûå ôàêòîðû, íàèáîëåå çíà÷èìûìè èç êîòîðûõ ñ÷èòàþòñÿ ïå÷ ̧íî÷íàÿ íåäîñòàòî÷íîñòü, ñàõàðíûé äèàáåò, òÿæ ̧ëûé ìåòàáîëè÷åñêèé àöèäîç, ãåðèàòðè÷åñêèé âîçðàñò, ñåðäå÷íàÿ íåäîñòàòî÷íîñòü, ïèòàíèå
    Exact
    [13– 15]
    Suffix
    . Áîëåå ïîçäíèå èññëåäîâàíèÿ ïîêàçàëè, ÷òî ìàêñèìàëüíûé ðîñò àöåòàòà â êðîâè âî âðåìÿ áèêàðáîíàòíîãî äèàëèçà îòìå÷àëñÿ ó áîëüíûõ ñ èñõîäíîé àöåòàòåìèåé.  òî æå âðåìÿ, âî âðåìÿ áåçàöåòàòíîãî äèàëèçà èñõîäíî âûñîêèé óðîâåíü àöåòàòà èìåë òåíäåíöèþ ê íîðìàëèçàöèè [9, 12].

14
Tolchin N, Roberts JL, Hayashi J, Lewis EJ. Metabolic consequences of high mass-transfer hemodialysis. Kidney International 1977; 11: 366-378
Total in-text references: 2
  1. In-text reference with the coordinate start=13076
    Prefix
    ±68141±46 Na, ммоль/л135,2±4,9136,±3,6132±6135±3 HCO3, ммоль/л24,2±2,825,9±3,926,1±1,826±2,2 Cl, ммоль/л102±4104±3101±7105±6 Лактат, ммоль/л2,1±0,91,9±1,22,2±1,22,4±1,4 àöåòàòà ìîãóò ñïîñîáñòâîâàòü ðàçëè÷íûå ôàêòîðû, íàèáîëåå çíà÷èìûìè èç êîòîðûõ ñ÷èòàþòñÿ ïå÷ ̧íî÷íàÿ íåäîñòàòî÷íîñòü, ñàõàðíûé äèàáåò, òÿæ ̧ëûé ìåòàáîëè÷åñêèé àöèäîç, ãåðèàòðè÷åñêèé âîçðàñò, ñåðäå÷íàÿ íåäîñòàòî÷íîñòü, ïèòàíèå
    Exact
    [13– 15]
    Suffix
    . Áîëåå ïîçäíèå èññëåäîâàíèÿ ïîêàçàëè, ÷òî ìàêñèìàëüíûé ðîñò àöåòàòà â êðîâè âî âðåìÿ áèêàðáîíàòíîãî äèàëèçà îòìå÷àëñÿ ó áîëüíûõ ñ èñõîäíîé àöåòàòåìèåé.  òî æå âðåìÿ, âî âðåìÿ áåçàöåòàòíîãî äèàëèçà èñõîäíî âûñîêèé óðîâåíü àöåòàòà èìåë òåíäåíöèþ ê íîðìàëèçàöèè [9, 12].

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    Prefix
    Íåïîñðåäñòâåííûìè ìåõàíèçìàìè ñ÷èòàþòñÿ èíäóêöèÿ ãèïîêñèè ñ ïîñëåäóþùåé àêòèâàöèåé ïðîâîñïàëèòåëüíîãî öèòîêèíîâîãî êàñêàäà, àêòèâàöèÿ öèêëîîêñèãåíàçû è ëèïîîêñèãåíàçû, ñèíòåç ïðîñòàãëàíäèíîâ è òðîìáîêñàíà
    Exact
    [11, 14,16]
    Suffix
    . Êðîìå òîãî, àöåòàò àêòèâèçèðóåò ìàññèâíîå âûñâîáîæäåíèå îêñèäà àçîòà (NO) ïîñðåäñòâîì ñòèìóëÿöèè ñèíòåçà èíäóöèáåëüíîé NO-ñèíòåòàçû, ÷òî âûçûâàåò ñíèæåíèå ïåðèôåðè÷åñêîãî ñîñóäèñòîãî ñîïðîòèâëåíèÿ [11, 17].

15
Tollinger CD, Vreman HJ, Weiner MW. Measurement of acetate in human blood by gas chromatography: effect of sample preparation, feeding, and various diseases. Clin Chem 1979; 25/10: 1787-1790
Total in-text references: 2
  1. In-text reference with the coordinate start=13076
    Prefix
    ±68141±46 Na, ммоль/л135,2±4,9136,±3,6132±6135±3 HCO3, ммоль/л24,2±2,825,9±3,926,1±1,826±2,2 Cl, ммоль/л102±4104±3101±7105±6 Лактат, ммоль/л2,1±0,91,9±1,22,2±1,22,4±1,4 àöåòàòà ìîãóò ñïîñîáñòâîâàòü ðàçëè÷íûå ôàêòîðû, íàèáîëåå çíà÷èìûìè èç êîòîðûõ ñ÷èòàþòñÿ ïå÷ ̧íî÷íàÿ íåäîñòàòî÷íîñòü, ñàõàðíûé äèàáåò, òÿæ ̧ëûé ìåòàáîëè÷åñêèé àöèäîç, ãåðèàòðè÷åñêèé âîçðàñò, ñåðäå÷íàÿ íåäîñòàòî÷íîñòü, ïèòàíèå
    Exact
    [13– 15]
    Suffix
    . Áîëåå ïîçäíèå èññëåäîâàíèÿ ïîêàçàëè, ÷òî ìàêñèìàëüíûé ðîñò àöåòàòà â êðîâè âî âðåìÿ áèêàðáîíàòíîãî äèàëèçà îòìå÷àëñÿ ó áîëüíûõ ñ èñõîäíîé àöåòàòåìèåé.  òî æå âðåìÿ, âî âðåìÿ áåçàöåòàòíîãî äèàëèçà èñõîäíî âûñîêèé óðîâåíü àöåòàòà èìåë òåíäåíöèþ ê íîðìàëèçàöèè [9, 12].

  2. In-text reference with the coordinate start=14586
    Prefix
    Ïîâûøåíèå óðîâíÿ àöåòàòà â 4–5 ðàç îò èñõîäíîãî (èëè â 12–13 ðàç îò íîðìû) è ðàíã êîëåáàíèé (ìàêñèìàëüíî äî 2,1 ììîëü/ë) ïðè èñïîëüçîâàíèè áèêàðáîíàòíîãî äèàëèçàòà òàêæå ñîãëàñóþòñÿ ñ ëèòåðàòóðíûìè äàííûìè
    Exact
    [9, 12, 15]
    Suffix
    . Ñëåäóåò îòäåëüíî îòìåòèòü, ÷òî â íàøåì èññëåäîâàíèè ó áîëüøèíñòâà áîëüíûõ èìåëèñü îäíîâðåìåííî íåñêîëüêî ôàêòîðîâ, âëèÿþùèõ íà ñêîðîñòü ìåòàáîëèçìà àöåòàòà. Îöåíêà ýôôåêòèâíîñòè êîððåêöèè ñàìîé ïî÷å÷íîé íåäîñòàòî÷íîñòè ïîêàçàëà îòñóòñòâèå çíà÷èìûõ ìåæãðóïïîâûõ ðàçëè÷èé.

16
Bolasco P, Ghezzi P M, Serra A, et al. Effects of acetatefree haemodiafiltration (HDF) with endogenous reinfusion (HFR) on cardiac troponin levels. Nephrol Dial Transplant 2011; 26(1): 258-263
Total in-text references: 1
  1. In-text reference with the coordinate start=13660
    Prefix
    Íåïîñðåäñòâåííûìè ìåõàíèçìàìè ñ÷èòàþòñÿ èíäóêöèÿ ãèïîêñèè ñ ïîñëåäóþùåé àêòèâàöèåé ïðîâîñïàëèòåëüíîãî öèòîêèíîâîãî êàñêàäà, àêòèâàöèÿ öèêëîîêñèãåíàçû è ëèïîîêñèãåíàçû, ñèíòåç ïðîñòàãëàíäèíîâ è òðîìáîêñàíà
    Exact
    [11, 14,16]
    Suffix
    . Êðîìå òîãî, àöåòàò àêòèâèçèðóåò ìàññèâíîå âûñâîáîæäåíèå îêñèäà àçîòà (NO) ïîñðåäñòâîì ñòèìóëÿöèè ñèíòåçà èíäóöèáåëüíîé NO-ñèíòåòàçû, ÷òî âûçûâàåò ñíèæåíèå ïåðèôåðè÷åñêîãî ñîñóäèñòîãî ñîïðîòèâëåíèÿ [11, 17].

17
Amore A, Cirina P, Mitola S et al. Acetate intolerance is mediated by enhanced synthesis of nitric oxide by endothelial cells. J Am Soc Nephrol 1997; 8: 1431–1436
Total in-text references: 1
  1. In-text reference with the coordinate start=13871
    Prefix
    Êðîìå òîãî, àöåòàò àêòèâèçèðóåò ìàññèâíîå âûñâîáîæäåíèå îêñèäà àçîòà (NO) ïîñðåäñòâîì ñòèìóëÿöèè ñèíòåçà èíäóöèáåëüíîé NO-ñèíòåòàçû, ÷òî âûçûâàåò ñíèæåíèå ïåðèôåðè÷åñêîãî ñîñóäèñòîãî ñîïðîòèâëåíèÿ
    Exact
    [11, 17]
    Suffix
    . Êëèíè÷åñêèì ïðîÿâëåíèåì ãåìîäèíàìè÷åñêèõ ýôôåêòîâ àöåòàòà ÿâëÿåòñÿ ñíèæåíèå ñèñòîëè÷åñêîãî è äèàñòîëè÷åñêîãî àðòåðèàëüíîãî äàâëåíèÿ â ñî÷åòàíèè ñ óâåëè÷åíèåì ÷àñòîòû ñåðäå÷íûõ ñîêðàùåíèé. Àíàëèç ðåçóëüòàòîâ íàøåãî èññëåäîâàíèÿ ïîêàçàë, ÷òî íàèáîëåå çíà÷èìûé ðîñò óðîâíÿ àöåòàòà ïîñëå SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì ðåãèñòðèðîâàëñÿ ó áîëüíûõ ñ îñòðîé ñåðäå÷íîé íåäîñòàòî÷íîñòüþ, íóæäàþùèõñÿ â èíîò

18
Мухоедова ТВ, Унароков ЗМ. Опыт применения sustained low efficiency dialysis (sled) – технологий заместительной почечной терапии в лечении кардиоренального синдрома с диуретик-рефрактерными отеками. Нефрология 2010; 14 (1): 63-67
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    Prefix
    Êðîìå òîãî, öåííûì ïðåèìóùåñòâîì áåçàöåòàòíîãî äèàëèçàòà íàìè âûÿâëåíî çíà÷èòåëüíî ìåíüøåå àðèòìîãåííîå âëèÿíèå, â òîì ÷èñëå óñóãóáëåíèå èñõîäíîé òàõèàðèòìèè, ïî ñðàâíåíèþ ñ òðàäèöèîííûì áèêàðáîíàòíûì äèàëèçàòîì. Ïîëó÷åííûå ðåçóëüòàòû ïîäòâåðæäàþò íàøè ïðåäâàðèòåëüíûå äàííûå î ïðåèìóùåñòâå áåçàöåòàòíîãî äèàëèçà â àñïåêòå ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè
    Exact
    [18, 19]
    Suffix
    . Îäíèì èç çíà÷èìûõ ôàêòîðîâ èíòðàäèàëèçíîé ñåðäå÷íî-ñîñóäèñòîé ñòàáèëüíîñòè ÿâëÿåòñÿ ñêîðîñòü è îáú ̧ì ÓÔ.  íàøåì èññëåäîâàíèè ïðåäïèñàííûé îáú ̧ì ÓÔ ó áîëüíûõ ñ ãèïåðãèäðàòàöèåé áûë äîñòèãíóò âî âñåõ ñëó÷àÿõ.

19
Mukhoedova T, Unarokov Z. Sustained low-efficiency daily dialysis with acetate-free dialysate in patient with acute kidney ingury after cardiac surgery. NDT Plus 2010; 3 (suppl 3): iii367
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    Êðîìå òîãî, öåííûì ïðåèìóùåñòâîì áåçàöåòàòíîãî äèàëèçàòà íàìè âûÿâëåíî çíà÷èòåëüíî ìåíüøåå àðèòìîãåííîå âëèÿíèå, â òîì ÷èñëå óñóãóáëåíèå èñõîäíîé òàõèàðèòìèè, ïî ñðàâíåíèþ ñ òðàäèöèîííûì áèêàðáîíàòíûì äèàëèçàòîì. Ïîëó÷åííûå ðåçóëüòàòû ïîäòâåðæäàþò íàøè ïðåäâàðèòåëüíûå äàííûå î ïðåèìóùåñòâå áåçàöåòàòíîãî äèàëèçà â àñïåêòå ãåìîäèíàìè÷åñêîé áåçîïàñíîñòè
    Exact
    [18, 19]
    Suffix
    . Îäíèì èç çíà÷èìûõ ôàêòîðîâ èíòðàäèàëèçíîé ñåðäå÷íî-ñîñóäèñòîé ñòàáèëüíîñòè ÿâëÿåòñÿ ñêîðîñòü è îáú ̧ì ÓÔ.  íàøåì èññëåäîâàíèè ïðåäïèñàííûé îáú ̧ì ÓÔ ó áîëüíûõ ñ ãèïåðãèäðàòàöèåé áûë äîñòèãíóò âî âñåõ ñëó÷àÿõ.

20
Tonelli M, Astephen P, Andreou P, Beed S. Blood volume monitoring in intermittent hemodialysis for acute renal failure. Kidney Int 2002; 62: 1075-1080
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    Prefix
    Äàííàÿ ôóíêöèÿ ïîçâîëÿåò ðåãóëèðîâàòü ñêîðîñòü ÓÔ â çàâèñèìîñòè îò ñêîðîñòè âîñïîëíåíèÿ ñîñóäèñòîãî ðóñëà èç èíòåðñòèöèÿ, â àâòîìàòè÷åñêîì ðåæèìå ëèáî âðó÷íóþ.  ëèòåðàòóðå íåò îäíîçíà÷íûõ ðåêîìåíäàöèé ïî âûáîðó áåçîïàñíîãî óðîâíÿ êðèòè÷åñêîãî ñíèæåíèÿ îòíîñèòåëüíîãî îáú ̧ìà êðîâè – RBV (Relative Blood Volume)
    Exact
    [20, 21]
    Suffix
    . Íà îñíîâàíèè íàøåãî îïûòà äëÿ ìèíèìèçàöèè âëèÿíèÿ ÓÔ íà ãåìîäèíàìè÷åñêóþ ñòàáèëüíîñòü, ìû âûáðàëè óðîâåíü êðèòè÷åñêîãî RBV= 95% (ò.å. óðîâåíü ñíèæåíèÿ îòíîñèòåëüíîãî îáú ̧ìà êðîâè ñîñòàâëÿë íå áîëåå 5%), ÷òî ñîîòâåòñòâîâàëî ñêîðîñòè îòðèöàòåëüíîãî âîäíîãî áàëàíñà 50–200 ìë/÷.

21
Locatelli F, Buoncristiani U, Canaud B et al. Haemodialysis with on-line monitoring equipment: tools or toys? Nephrol Dial Transplant 2005; 20(1): 22-33
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    Äàííàÿ ôóíêöèÿ ïîçâîëÿåò ðåãóëèðîâàòü ñêîðîñòü ÓÔ â çàâèñèìîñòè îò ñêîðîñòè âîñïîëíåíèÿ ñîñóäèñòîãî ðóñëà èç èíòåðñòèöèÿ, â àâòîìàòè÷åñêîì ðåæèìå ëèáî âðó÷íóþ.  ëèòåðàòóðå íåò îäíîçíà÷íûõ ðåêîìåíäàöèé ïî âûáîðó áåçîïàñíîãî óðîâíÿ êðèòè÷åñêîãî ñíèæåíèÿ îòíîñèòåëüíîãî îáú ̧ìà êðîâè – RBV (Relative Blood Volume)
    Exact
    [20, 21]
    Suffix
    . Íà îñíîâàíèè íàøåãî îïûòà äëÿ ìèíèìèçàöèè âëèÿíèÿ ÓÔ íà ãåìîäèíàìè÷åñêóþ ñòàáèëüíîñòü, ìû âûáðàëè óðîâåíü êðèòè÷åñêîãî RBV= 95% (ò.å. óðîâåíü ñíèæåíèÿ îòíîñèòåëüíîãî îáú ̧ìà êðîâè ñîñòàâëÿë íå áîëåå 5%), ÷òî ñîîòâåòñòâîâàëî ñêîðîñòè îòðèöàòåëüíîãî âîäíîãî áàëàíñà 50–200 ìë/÷.

22
Marshall MR, Golper TA, Shaver MJ et al. Sustained low-efficiency dialysis for critically ill patients requiring renal replacement therapy. Kidney Int 2001; 60: 777-785
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    Ñëåäóåò îòìåòèòü, ÷òî ÷àñòîòà çàðåãèñòðèðîâàííûõ â íàøåì èññëåäîâàíèè îñëîæíåíèé â ãðóïïå SLEDD ñ áèêàðáîíàòíûì äèàëèçàòîì (19,5%) ñîïîñòàâèìà ñ äàííûìè çàðóáåæíûõ èññëåäîâàíèé. Òàê, â èññëåäîâàíèè M.R. Marshal è ñîàâò.
    Exact
    [22]
    Suffix
    ó ïîëîâèíû áîëüíûõ, ïîëó÷àâøèõ èíîòðîïíóþ ïîääåðæêó, âî âðåìÿ òåðàïèè ïðèõîäèëîñü óâåëè÷èâàòü äîçó ýòèõ ïðåïàðàòîâ, â ñðåäíåì íà 66,7%. Âî âðåìÿ 20 èç 145 ïðîöåäóð íàáëþäàëèñü îäèí èëè íåñêîëüêî ýïèçîäîâ ãèïîòåíçèè, à â 7% ñëó÷àåâ ëå÷åíèå áûëî äîñðî÷íî ïðåðâàíî èç-çà òÿæ ̧ëîé ãèïîòåíçèè.

23
Birne R, Branco P, Marcelino P et al. A comparative study of cardiovascular tolerability with slow extended dialysis versus continuous haemodiafiltration in the critical patient. Port J Nephrol Hypert 2009; 23(4): 323-330
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  1. In-text reference with the coordinate start=17563
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    Marshal è ñîàâò. [22] ó ïîëîâèíû áîëüíûõ, ïîëó÷àâøèõ èíîòðîïíóþ ïîääåðæêó, âî âðåìÿ òåðàïèè ïðèõîäèëîñü óâåëè÷èâàòü äîçó ýòèõ ïðåïàðàòîâ, â ñðåäíåì íà 66,7%. Âî âðåìÿ 20 èç 145 ïðîöåäóð íàáëþäàëèñü îäèí èëè íåñêîëüêî ýïèçîäîâ ãèïîòåíçèè, à â 7% ñëó÷àåâ ëå÷åíèå áûëî äîñðî÷íî ïðåðâàíî èç-çà òÿæ ̧ëîé ãèïîòåíçèè.  èññëåäîâàíèè R. Birne è ñîàâò.
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    [23]
    Suffix
    ãåìîäèíàìè÷åñêèå îñëîæíåíèÿ çàðåãèñòðèðîâàíû âî âðåìÿ 28% ñåàíñîâ SLED, â 12% ñëó÷àåâ ëå÷åíèå òàêæå áûëî ïðåðâàíî äîñðî÷íî. Ýòè è àíàëîãè÷íûå ðåçóëüòàòû â äðóãèõ ïóáëèêàöèÿõ ïîäòâåðæäàþò, ÷òî ïîèñê ïóòåé óâåëè÷åíèÿ áåçîïàñíîñòè SLED ó áîëüíûõ â êðèòè÷åñêèõ ñîñòîÿíèÿõ îñòà ̧òñÿ àêòóàëüíûì [24–27].

24
Naka T, Baldwin I, Bellomo R et al. Prolonged daily intermittent renal replacement therapy in ICU patients by ICU nurses and ICU physicians. Int J Artif Organs 2004; 27(5): 380387
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    Birne è ñîàâò. [23] ãåìîäèíàìè÷åñêèå îñëîæíåíèÿ çàðåãèñòðèðîâàíû âî âðåìÿ 28% ñåàíñîâ SLED, â 12% ñëó÷àåâ ëå÷åíèå òàêæå áûëî ïðåðâàíî äîñðî÷íî. Ýòè è àíàëîãè÷íûå ðåçóëüòàòû â äðóãèõ ïóáëèêàöèÿõ ïîäòâåðæäàþò, ÷òî ïîèñê ïóòåé óâåëè÷åíèÿ áåçîïàñíîñòè SLED ó áîëüíûõ â êðèòè÷åñêèõ ñîñòîÿíèÿõ îñòà ̧òñÿ àêòóàëüíûì
    Exact
    [24–27]
    Suffix
    . Íàøè äàííûå ïîäòâåðæäàþò, ÷òî èñêëþ÷åíèå äàæå íåáîëüøîãî ñîäåðæàíèÿ àöåòàòà â äèàëèçèðóþùåì ðàñòâîðå ÿâëÿåòñÿ îäíèì èç ñïîñîáîâ óâåëè÷åíèÿ ãåìîäèíàìè÷åñêîé òîëåðàíòíîñòè áîëüíûõ íå òîëüêî ñ òåðìèíàëüíîé ÕÏÍ, íî è ñ ÎÏÏ, ê èíòåðìèòòèðóþùèì ìåòîäàì ÇÏÒ.

25
Yegenaga I, Vanholder R, Hoste E et al. Studу of hemodynamic disturbances during slow extended daily hemodialysis vs continuous renal replacement therapy in acute renal failure patients in the intensive care unit. Blood Purif 2004; 22: 240-241
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    Birne è ñîàâò. [23] ãåìîäèíàìè÷åñêèå îñëîæíåíèÿ çàðåãèñòðèðîâàíû âî âðåìÿ 28% ñåàíñîâ SLED, â 12% ñëó÷àåâ ëå÷åíèå òàêæå áûëî ïðåðâàíî äîñðî÷íî. Ýòè è àíàëîãè÷íûå ðåçóëüòàòû â äðóãèõ ïóáëèêàöèÿõ ïîäòâåðæäàþò, ÷òî ïîèñê ïóòåé óâåëè÷åíèÿ áåçîïàñíîñòè SLED ó áîëüíûõ â êðèòè÷åñêèõ ñîñòîÿíèÿõ îñòà ̧òñÿ àêòóàëüíûì
    Exact
    [24–27]
    Suffix
    . Íàøè äàííûå ïîäòâåðæäàþò, ÷òî èñêëþ÷åíèå äàæå íåáîëüøîãî ñîäåðæàíèÿ àöåòàòà â äèàëèçèðóþùåì ðàñòâîðå ÿâëÿåòñÿ îäíèì èç ñïîñîáîâ óâåëè÷åíèÿ ãåìîäèíàìè÷åñêîé òîëåðàíòíîñòè áîëüíûõ íå òîëüêî ñ òåðìèíàëüíîé ÕÏÍ, íî è ñ ÎÏÏ, ê èíòåðìèòòèðóþùèì ìåòîäàì ÇÏÒ.

26
Lima EQ, Fernandes A, Zanon J et al. Preventing intradialytic hypotension in acute kidney ingury patients submitted to slow low efficiency dialysis (SLED). Blood Purif 2008; 26: 179-180
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    Prefix
    Birne è ñîàâò. [23] ãåìîäèíàìè÷åñêèå îñëîæíåíèÿ çàðåãèñòðèðîâàíû âî âðåìÿ 28% ñåàíñîâ SLED, â 12% ñëó÷àåâ ëå÷åíèå òàêæå áûëî ïðåðâàíî äîñðî÷íî. Ýòè è àíàëîãè÷íûå ðåçóëüòàòû â äðóãèõ ïóáëèêàöèÿõ ïîäòâåðæäàþò, ÷òî ïîèñê ïóòåé óâåëè÷åíèÿ áåçîïàñíîñòè SLED ó áîëüíûõ â êðèòè÷åñêèõ ñîñòîÿíèÿõ îñòà ̧òñÿ àêòóàëüíûì
    Exact
    [24–27]
    Suffix
    . Íàøè äàííûå ïîäòâåðæäàþò, ÷òî èñêëþ÷åíèå äàæå íåáîëüøîãî ñîäåðæàíèÿ àöåòàòà â äèàëèçèðóþùåì ðàñòâîðå ÿâëÿåòñÿ îäíèì èç ñïîñîáîâ óâåëè÷åíèÿ ãåìîäèíàìè÷åñêîé òîëåðàíòíîñòè áîëüíûõ íå òîëüêî ñ òåðìèíàëüíîé ÕÏÍ, íî è ñ ÎÏÏ, ê èíòåðìèòòèðóþùèì ìåòîäàì ÇÏÒ.

27
Fieghen HE, Friedrich JO, Burns KE et al. The hemodynamic tolerability and feasibility of sustained low efficiency dialysis in the management of critically ill patients with acute kidney injury. BMC Nephrol 2010; 11: 32 Ïîñòóïèëà â ðåäàêöèþ 12.10.2011 ã.
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    Birne è ñîàâò. [23] ãåìîäèíàìè÷åñêèå îñëîæíåíèÿ çàðåãèñòðèðîâàíû âî âðåìÿ 28% ñåàíñîâ SLED, â 12% ñëó÷àåâ ëå÷åíèå òàêæå áûëî ïðåðâàíî äîñðî÷íî. Ýòè è àíàëîãè÷íûå ðåçóëüòàòû â äðóãèõ ïóáëèêàöèÿõ ïîäòâåðæäàþò, ÷òî ïîèñê ïóòåé óâåëè÷åíèÿ áåçîïàñíîñòè SLED ó áîëüíûõ â êðèòè÷åñêèõ ñîñòîÿíèÿõ îñòà ̧òñÿ àêòóàëüíûì
    Exact
    [24–27]
    Suffix
    . Íàøè äàííûå ïîäòâåðæäàþò, ÷òî èñêëþ÷åíèå äàæå íåáîëüøîãî ñîäåðæàíèÿ àöåòàòà â äèàëèçèðóþùåì ðàñòâîðå ÿâëÿåòñÿ îäíèì èç ñïîñîáîâ óâåëè÷åíèÿ ãåìîäèíàìè÷åñêîé òîëåðàíòíîñòè áîëüíûõ íå òîëüêî ñ òåðìèíàëüíîé ÕÏÍ, íî è ñ ÎÏÏ, ê èíòåðìèòòèðóþùèì ìåòîäàì ÇÏÒ.